Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.61 |
| ▸ | BTK | Q06187 | 1/20 | 0.55 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.53 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29094597 | 0.90 | EGFR (0.58) | EGFRBTKALKMAP4K1 | |
| SCHEMBL23420454 | 0.90 | EGFR (0.67) | EGFRBTKMAP4K1 | |
| SCHEMBL23442001 | 0.90 | EGFR (0.69) | EGFRBTKALK | |
| SCHEMBL23420406 | 0.89 | EGFR (0.68) | EGFRBTK | |
| SCHEMBL23442858 | 0.88 | EGFR (0.66) | EGFRBTKALK | |
| SCHEMBL25001601 | 0.87 | EGFR (0.57) | EGFRBTK | |
| SCHEMBL23421131 | 0.86 | EGFR (0.61) | EGFRBTK | |
| SCHEMBL25001799 | 0.86 | EGFR (0.65) | EGFR | |
| Hydrochloric Acid SCHEMBL31155488 | 0.86 | EGFR (0.60) | EGFRBTK | |
| SCHEMBL23442894 | 0.85 | EGFR (0.62) | EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021104441-A1 | POLYAROMATIC COMPOUND AS EGFR KINASE INHIBITOR | 江苏先声药业有限公司 | 2021-06-03 | — | — | WO | disclosed |