Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.58 |
| ▸ | BTK | Q06187 | 1/20 | 0.56 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31155488 | 0.94 | EGFR (0.60) | EGFRBTK | |
| SCHEMBL23420454 | 0.92 | EGFR (0.67) | EGFRBTKMAP4K1 | |
| SCHEMBL29094586 | 0.92 | EGFR (0.54) | EGFRBTKMAP4K1 | |
| SCHEMBL29094520 | 0.91 | EGFR (0.63) | EGFRBTKMAP4K1 | |
| Hydrochloric Acid SCHEMBL29094650 | 0.91 | EGFR (0.63) | EGFRBTKMAP4K1 | |
| SCHEMBL23420406 | 0.90 | EGFR (0.68) | EGFRBTK | |
| SCHEMBL23442859 | 0.90 | EGFR (0.61) | EGFRBTKMAP4K1ALK | |
| SCHEMBL23442001 | 0.89 | EGFR (0.69) | EGFRBTKALK | |
| SCHEMBL31155448 | 0.89 | EGFR (0.54) | EGFRBTK | |
| Hydrochloric Acid SCHEMBL29094608 | 0.89 | EGFR (0.50) | EGFRBTKMAP4K1ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116891502-A | EGFR degrading agent | 上海齐鲁制药研究中心有限公司 | 2023-10-17 | — | — | CN | disclosed |