Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.57 |
| ▸ | GAK | O14976 | 2/20 | 0.57 |
| ▸ | ERBB2 | P04626 | 14/20 | 0.55 |
| ▸ | STK4 | Q13043 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18933465 | 0.78 | EGFR (0.64) | EGFRGAKERBB2STK4 | |
| SCHEMBL29670931 | 0.75 | STK4 (0.81) | EGFRGAKERBB2STK4 | |
| SCHEMBL28503961 | 0.75 | STK4 (0.81) | EGFRGAKERBB2STK4 | |
| SCHEMBL30390074 | 0.75 | STK4 (0.81) | EGFRGAKERBB2STK4 | |
| Hydrochloric Acid SCHEMBL28499414 | 0.75 | STK4 (0.80) | EGFRGAKERBB2STK4 | |
| SCHEMBL28494494 | 0.75 | STK4 (0.69) | EGFRGAKERBB2STK4 | |
| Hydrochloric Acid SCHEMBL29670929 | 0.75 | STK4 (0.80) | EGFRGAKERBB2STK4 | |
| SCHEMBL29670937 | 0.75 | STK4 (0.69) | EGFRGAKERBB2STK4 | |
| SCHEMBL30390357 | 0.74 | STK4 (0.70) | EGFRGAKERBB2STK4 | |
| SCHEMBL29670935 | 0.73 | EGFR (0.67) | EGFRGAKERBB2STK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021104340-A1 | SUBSTITUTED CROTONAMIDE PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD THEREFOR | 江苏苏中药业集团股份有限公司 | 2021-06-03 | — | — | WO | disclosed |