Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 5/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
| ▸ | MDM4 | O15151 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19602150 | 1.00 | TLR2 (0.52) | TLR2MDM2KMT2ATLR1CA1 | |
| SCHEMBL23446479 | 0.96 | TLR2 (0.53) | TLR2MDM2KMT2ATLR1CXCR3 | |
| SCHEMBL30895590 | 0.93 | MDM2 (0.55) | TLR2MDM2KMT2ATLR1CXCR3 | |
| SCHEMBL9933933 | 0.93 | MDM2 (0.55) | TLR2MDM2KMT2ATLR1CXCR3 | |
| SCHEMBL16328803 | 0.93 | TLR2 (0.59) | TLR2MDM2KMT2ATLR1 | |
| SCHEMBL30972264 | 0.92 | CASP3 (0.49) | TLR2MDM2KMT2ATLR1CA1 | |
| SCHEMBL30895597 | 0.92 | MDM2 (0.54) | TLR2MDM2KMT2ATLR1CXCR3 | |
| SCHEMBL29386955 | 0.92 | MDM2 (0.56) | TLR2MDM2KMT2ATLR1MDM4 | |
| SCHEMBL17002047 | 0.92 | MDM2 (0.51) | TLR2MDM2KMT2ATLR1CA1 | |
| SCHEMBL16185928 | 0.92 | TLR2 (0.53) | TLR2MDM2KMT2ATLR1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021104120-A1 | POLYETHYLENE GLYCOL CONJUGATE MEDICAMENT, PREPARATION METHOD THERFOR AND USE THEREOF | 重庆阿普格雷生物科技有限公司 | 2021-06-03 | — | — | WO | disclosed |