Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26739746 | 0.84 | MAPT (0.45) | CNR2KMT2AMAPTGAAKDM4E | |
| SCHEMBL4082936 | 0.84 | KCNQ3 (0.48) | CNR2KMT2AMAPTGAAKDM4E | |
| SCHEMBL13006763 | 0.83 | MAPT (0.49) | CNR2MAPTGAAKDM4EALDH1A1 | |
| SCHEMBL12845203 | 0.81 | RAB9A (0.57) | KMT2AMAPTGAAKDM4ERAB9A | |
| SCHEMBL2790485 | 0.80 | MAPT (0.58) | KMT2AMAPTDGAT1GAAKDM4E | |
| SCHEMBL24590407 | 0.79 | MAPT (0.55) | KMT2AMAPTDGAT1GAAKDM4E | |
| SCHEMBL26739734 | 0.78 | MAPT (0.43) | CNR2KMT2AMAPTDGAT1GAA | |
| SCHEMBL15183915 | 0.78 | KDM4E (0.52) | KMT2AMAPTGAAKDM4ERAB9A | |
| SCHEMBL14376100 | 0.77 | GRIN2D (0.51) | CNR2KMT2AMAPTGAAKDM4E | |
| SCHEMBL4377962 | 0.77 | MAPT (0.68) | MAPTDGAT1KDM4ERAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021108803-A1 | FUSED PYRIMIDINE PYRIDINONE COMPOUNDS AS JAK INHIBITORS | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2021-06-03 | — | — | WO | disclosed |