SCHEMBL23447002

SCHEMBL23447002

Cc1c(Cl)cccc1NC(=O)Nc1ccc2c(c1O)S(=O)(=O)CC=C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 19/20 1.00
TRPV1 Q8NER1 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23447004 0.90 CXCR2 (1.00) CXCR2
SCHEMBL23447850 0.89 CXCR2 (1.00) CXCR2
SCHEMBL23446995 0.87 CXCR2 (1.00) CXCR2
SCHEMBL29862638 0.83 CXCR2 (1.00) CXCR2
SCHEMBL23447007 0.83 CXCR2 (1.00) CXCR2
SCHEMBL23447005 0.81 CXCR2 (1.00) CXCR2TRPV1
SCHEMBL23447001 0.80 CXCR2 (1.00) CXCR2
SCHEMBL23446996 0.80 CXCR2 (1.00) CXCR2
SCHEMBL23446999 0.77 CXCR2 (1.00) CXCR2TRPV1
SCHEMBL23447014 0.77 CXCR2 (1.00) CXCR2TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021104506-A1 CYCLIC SULFONE COMPOUND AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 中国医学科学院药物研究所 2021-06-03 WO disclosed