Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23447638 | 0.98 | SLC6A3 (0.61) | SLC6A3SLC6A4KDM4ENPSR1MAPT | |
| SCHEMBL23447126 | 0.90 | SLC6A4 (0.51) | SLC6A3SLC6A4KDM4ENPSR1MAPT | |
| SCHEMBL23409686 | 0.88 | MAPT (0.53) | SLC6A3SLC6A4KDM4ENPSR1MAPT | |
| SCHEMBL23447591 | 0.86 | MAPT (0.52) | SLC6A3SLC6A4KDM4ENPSR1MAPT | |
| SCHEMBL23447380 | 0.85 | MAPT (0.46) | SLC6A3SLC6A4KDM4ENPSR1MAPT | |
| SCHEMBL23447363 | 0.84 | KDM4E (0.47) | SLC6A3SLC6A4KDM4ENPSR1MAPT | |
| SCHEMBL23447371 | 0.83 | IKBKB (0.49) | SLC6A3SLC6A4KDM4ENPSR1MAPT | |
| SCHEMBL23447360 | 0.81 | KDM4E (0.44) | SLC6A3SLC6A4KDM4ENPSR1MAPT | |
| SCHEMBL23447597 | 0.79 | MAPT (0.52) | SLC6A3SLC6A4KDM4ENPSR1MAPT | |
| SCHEMBL23447119 | 0.79 | MAPT (0.51) | KDM4ENPSR1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230046046-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-02-16 | — | — | US | disclosed |
| WO-2021104749-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230046046-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | ETV6, CYP2C19, ESR1 | SLC6A3 886/4885SLC6A4 3014/4885KDM4E 2646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.