SCHEMBL2344909

SCHEMBL2344909

CNC(=O)c1ccccc1C(=O)NC

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.71
PLK1 P53350 2/20 0.65
BRD4 O60885 3/20 0.50
KAT2B Q92831 1/20 0.49
BAZ2B Q9UIF8 1/20 0.49
BRD2 P25440 1/20 0.49
BRD3 Q15059 1/20 0.49
BRDT Q58F21 1/20 0.49
SLC6A2 P23975 1/20 0.49
SLC6A4 P31645 1/20 0.49
SLC6A3 Q01959 1/20 0.49
POLB P06746 1/20 0.49
TSHR P16473 1/20 0.48
HTT P42858 1/20 0.48
MAPK10 P53779 1/20 0.47
KMT2A Q03164 1/20 0.47
APEX1 P27695 1/20 0.47
ALDH1A1 P00352 2/20 0.46
RECQL P46063 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5738608 0.93 GAA (0.63) GAAPLK1BRD4KAT2BBAZ2B
SCHEMBL13945832 0.91 GAA (0.61) GAAPLK1BRD4KAT2BBAZ2B
SCHEMBL278615 0.91 ALDH1A1 (0.64) GAAPLK1POLBHTTKMT2A
SCHEMBL4666198 0.89 GAA (0.59) GAAPLK1BRD4TSHRALDH1A1
Hydrochloric Acid SCHEMBL6885250 0.89 ALDH1A1 (0.61) GAAPLK1POLBHTTKMT2A
SCHEMBL30064209 0.89 GAA (0.59) GAAPLK1BRD4TSHRALDH1A1
SCHEMBL11410287 0.87 GAA (0.63) GAAPLK1BRD4KAT2BBAZ2B
SCHEMBL23864393 0.87 GAA (0.57) GAAPLK1BRD4KAT2BBAZ2B
SCHEMBL11504870 0.87 AKR1C3 (0.63) GAAPLK1POLBMAPK10KMT2A
Hydrochloric Acid SCHEMBL30576696 0.87 GAA (0.57) GAAPLK1BRD4TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0639588-B1 Process for the manufacture of weak basic anion exchange resins and reagents therefor BAYER AG (DE) 1998-01-07 EP claimed
US-5464875-A Process for preparing weakly-basic anion exchangers and reagents suitable for this purpose BAYER AKTIENGESELLSCHAFT (DE) 1995-11-07 US claimed
EP-0639588-A1 Process for the manufacture of weak basic anion exchange resins and reagents therefor BAYER AG (DE) 1995-02-22 EP claimed
EP-3807369-B1 FLUOROPOLYMER COMPOSITIONS COMPRISING FLUORINATED ADDITIVES, COATED SUBSTRATES AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-07-24 EP disclosed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
US-20240227357-A1 Fluoropolymer Compositions and Methods Suitable for Copper Substrates and Electronic Telecommunications Articles 3M INNOVATIVE PROPERTIES COMPANY 2024-07-11 US disclosed
US-12018144-B2 Fluoropolymer coating compositions comprising amine curing agents, coated substrates and related methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-06-25 US disclosed
US-20240052191-A1 Electronic Telecommunications Articles Comprising Crosslinked Fluoropolymer and Fluoropolymer Particles, Compositions and Methods 3M INNOVATIVE PROPERTIES COMPANY 2024-02-15 US disclosed
US-11866602-B2 Fluoropolymer compositions comprising fluorinated additives, coated substrates and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-01-09 US disclosed
EP-3807344-B1 FLUOROPOLYMER COATING COMPOSITIONS COMPRISING AMINOSILANE CURING AGENTS, COATED SUBSTRATES AND RELATED METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-12-27 EP disclosed
EP-1263857-A2 CURABLE PERFLUOROELASTOMER COMPOSITION DUPONT DOW ELASTOMERS L.L.C. (US) 2002-12-11 EP disclosed
US-20020026014-A1 Curable perfluoroelastomer composition DUPONT POLYMERS, INC. 2002-02-28 US disclosed
US-6348599-B1 CYANINE DYES HAVING OVERALL POSITIVE CHARGE OF +2 TO +6 AND REACTIVE OR FUNCTIONAL GROUP PRESENT WHICH CAN REACT WITH FUNCTIONAL OR REACTIVE GROUP OF TARGET MOLECULE NYCOMED AMERSHAM PLC (GB) 2002-02-19 US disclosed
WO-2001059005-A2 CURABLE PERFLUOROELASTOMER COMPOSITION DUPONT DOW ELASTOMERS L.L.C. (US) 2001-08-16 WO disclosed
EP-1037947-A1 CYANINE DYES Nycomed Amersham plc (GB) 2000-09-27 EP disclosed
WO-1999005221-A1 CYANINE DYES NYCOMED AMERSHAM PLC (GB) 1999-02-04 WO disclosed
EP-0639588-B1 Process for the manufacture of weak basic anion exchange resins and reagents therefor BAYER AG (DE) 1998-01-07 EP disclosed
US-5464875-A Process for preparing weakly-basic anion exchangers and reagents suitable for this purpose BAYER AKTIENGESELLSCHAFT (DE) 1995-11-07 US disclosed
EP-0639588-A1 Process for the manufacture of weak basic anion exchange resins and reagents therefor BAYER AG (DE) 1995-02-22 EP disclosed