Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR1F | P30939 | 1/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23449269 | 0.80 | ADORA2B (0.43) | HTR1AHTR1DHTR1BHTR1FFGFR1 | |
| SCHEMBL30110633 | 0.78 | GRIN1 (0.48) | HTR1AHTR1DHTR1BHTR1FALDH1A1 | |
| SCHEMBL23393003 | 0.78 | GRIN1 (0.48) | HTR1AHTR1DHTR1BHTR1FALDH1A1 | |
| SCHEMBL12432879 | 0.72 | KDM4E (0.41) | CRHR1CRHR2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30012877 | 0.71 | TLR7 (0.40) | BTK | |
| SCHEMBL12432959 | 0.71 | CYP1A2 (0.43) | PDE5APRKDCALDH1A1KDM4ETSHR | |
| SCHEMBL23449145 | 0.70 | PDE5A (0.39) | CRHR1PDE5APDE4APDE4BPDE4C | |
| SCHEMBL23449146 | 0.69 | ADORA2B (0.40) | FGFR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL15168798 | 0.69 | PARG (0.42) | CRHR1CRHR2PDE5APDE4APDE4B | |
| SCHEMBL16510949 | 0.68 | PARG (0.40) | CRHR1CRHR2PDE5APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021108649-A1 | TLR7 AGONISTS | Primmune Therapeutics, Inc. (US) | 2021-06-03 | — | — | WO | disclosed |