Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23452096 | 0.93 | HDAC6 (0.49) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL18573454 | 0.78 | HDAC6 (0.55) | KDM4EALDH1A1HPGDSHMT2MAPT | |
| SCHEMBL23452054 | 0.77 | KDM4E (0.61) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL2157496 | 0.76 | MAPT (0.76) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL23452097 | 0.75 | NPSR1 (0.56) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL23452115 | 0.74 | IKBKB (0.53) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL23452104 | 0.74 | KDM4E (0.54) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL23452022 | 0.74 | IKBKB (0.63) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL613270 | 0.73 | KDM4E (0.57) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL15940345 | 0.72 | PRKCZ (0.58) | KDM4EALDH1A1HPGDSHMT2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079943-A | Method for synthesizing chiral cyano-containing full-carbon quaternary carbon cyclic compound | — | 2026-05-26 | — | — | CN | disclosed |
| CN-119080791-B | Construction of 1, 3-dioxolane derivatives by catalyzing electron-deficient alkenyl ethylene oxide through Lewis base | 山东第一医科大学(山东省医学科学院) | 2025-01-24 | — | — | CN | disclosed |
| CN-119080767-A | Indazole [3,2-a ] isoquinoline compounds with anticancer activity and synthesis method thereof | 河南师范大学 | 2024-12-06 | — | — | CN | disclosed |
| CN-119080791-A | Construction of 1, 3-dioxolane derivatives by catalyzing electron-deficient alkenyl ethylene oxide through Lewis base | 山东第一医科大学(山东省医学科学院) | 2024-12-06 | — | — | CN | disclosed |
| CN-118184565-A | Method for constructing all-carbon quaternary carbon center through 2, 3-disubstituted indole C6 functionalization | 中国科学院大连化学物理研究所 | 2024-06-14 | — | — | CN | disclosed |
| CN-118164950-A | Preparation method of chiral alkenyl thioflavonoid derivative and chiral alkenyl thioflavonoid derivative | 中国科学院大连化学物理研究所 | 2024-06-11 | — | — | CN | disclosed |
| CN-118164943-A | Axis chiral alkenyl flavonoid derivative and preparation method thereof | 中国科学院大连化学物理研究所 | 2024-06-11 | — | — | CN | disclosed |
| CN-117586266-A | Indenopyrazoles compounds with anticancer activity and synthesis method thereof | 河南师范大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-117026251-A | Electrochemical cyclization method of alkynyl phosphonate | 成都大学 | 2023-11-10 | — | — | CN | disclosed |
| CN-117024415-A | Synthesis method of 3-pyridine-4-enol substituted isocoumarin compound | 河南师范大学 | 2023-11-10 | — | — | CN | disclosed |
| CN-116640139-A | Method for synthesizing chiral indolizidine compound through [3+2] cycloaddition | 河南师范大学 | 2023-08-25 | — | — | CN | disclosed |
| CN-110981919-B | Method for synthesizing octatomic amidine cyclic palladium compound by one-pot method and application thereof | 郑州轻工业大学 | 2022-10-18 | — | — | CN | disclosed |
| US-11427596-B2 | Metal-free solvent-free synthesis of fused-pyrido heterocycles and biomedical applications | Indian Institute of Technology Indore (IN) | 2022-08-30 | — | — | US | disclosed |
| CN-114874140-A | Cyclic imine derivative with acrylate structure and preparation method thereof | 吉林大学 | 2022-08-09 | — | — | CN | disclosed |
| CN-114634490-A | Method for synthesizing heterotriarylmethane by functionalizing 2, 3-disubstituted indole C6 | 中国科学院大连化学物理研究所 | 2022-06-17 | — | — | CN | disclosed |
| US-11306103-B2 | Thieno[3,2-b]pyridine-5(4H)-one derivative compound, preparation method thereof and use thereof | KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY | 2022-04-19 | — | — | US | disclosed |
| US-11306103-B2 | Thieno[3,2-b]pyridine-5(4H)-one derivative compound, preparation method thereof and use thereof | KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY | 2022-04-19 | — | — | US | disclosed |
| US-20210171539-A1 | NOVEL THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KR) | 2021-06-10 | — | — | US | disclosed |
| US-20210171539-A1 | NOVEL THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KR) | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11427596-B2 | Metal-free solvent-free synthesis of fused-pyrido heterocycles and biomedical applications | SLC11A2, WEE1, BRCA1 | KDM4E 1717/4885ALDH1A1 2132/4885HPGD 1396/4885 |
| US-20210171539-A1 | NOVEL THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | BRD4, BRPF3, AFF4 | KDM4E 125/4885ALDH1A1 908/4885HPGD 2423/4885 |
| US-11306103-B2 | Thieno[3,2-b]pyridine-5(4H)-one derivative compound, preparation method thereof and use thereof | BRD4, BRPF3, AFF4 | KDM4E 159/4885ALDH1A1 921/4885HPGD 2657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.