Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1087617 | 0.81 | EPHX2 (0.41) | KDM4ELMNAALDH1A1EPHX2POLB | |
| SCHEMBL1089531 | 0.79 | KDM4E (0.41) | KDM4ELMNAALDH1A1EPHX2POLB | |
| SCHEMBL26935789 | 0.78 | EPHX2 (0.38) | KDM4ELMNAALDH1A1EPHX2POLB | |
| SCHEMBL4379431 | 0.77 | KDM4E (0.38) | KDM4ELMNAALDH1A1EPHX2POLB | |
| SCHEMBL13019213 | 0.77 | KDM4E (0.38) | KDM4ELMNAALDH1A1EPHX2POLB | |
| SCHEMBL4377524 | 0.77 | KDM4E (0.41) | KDM4ELMNAALDH1A1EPHX2POLB | |
| SCHEMBL4739740 | 0.76 | KDM4E (0.40) | KDM4ELMNAALDH1A1EPHX2POLB | |
| SCHEMBL3675886 | 0.75 | KDM4E (0.43) | KDM4ELMNAALDH1A1EPHX2POLB | |
| SCHEMBL8464466 | 0.75 | KDM4E (0.42) | KDM4ELMNAALDH1A1EPHX2POLB | |
| SCHEMBL15498477 | 0.75 | KDM4E (0.41) | KDM4ELMNAALDH1A1EPHX2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021105723-A1 | NOVEL LINKER COMPOUNDS | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2021-06-03 | — | — | WO | disclosed |