Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAE1 | Q13564 | 16/20 | 0.40 |
| ▸ | UBA3 | Q8TBC4 | 16/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 16/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 16/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23456248 | 0.85 | TYMP (0.37) | NAE1UBA3SAE1UBA2TYMP | |
| SCHEMBL23456067 | 0.83 | ACP1 (0.39) | NAE1UBA3SAE1UBA2TYMP | |
| SCHEMBL22401404 | 0.83 | ACP1 (0.39) | NAE1UBA3SAE1UBA2TYMP | |
| SCHEMBL23456027 | 0.77 | TYMP (0.36) | NAE1UBA3TYMP | |
| SCHEMBL23456061 | 0.75 | TYMP (0.36) | NAE1UBA3SAE1UBA2TYMP | |
| SCHEMBL23456175 | 0.74 | TYMP (0.37) | NAE1UBA3TYMP | |
| SCHEMBL23455991 | 0.74 | TYMP (0.37) | NAE1UBA3SAE1UBA2TYMP | |
| SCHEMBL23456070 | 0.74 | NAE1 (0.34) | NAE1UBA3TYMP | |
| SCHEMBL27250645 | 0.73 | SAE1 (0.36) | NAE1UBA3SAE1UBA2 | |
| SCHEMBL23455989 | 0.73 | NAE1 (0.40) | NAE1UBA3TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12054512-B2 | Sting modulator compounds, and methods of making and using | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-08-06 | — | — | US | disclosed |
| US-20240209017-A1 | STING MODULATOR COMPOUNDS, AND METHODS OF MAKING AND USING | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-06-27 | — | — | US | disclosed |
| US-11542293-B2 | Sting modulator compounds, and methods of making and using | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-01-03 | — | — | US | disclosed |
| EP-3707151-B1 | STING MODULATOR COMPOUNDS, AND METHODS OF MAKING AND USING | TAKEDA PHARMACEUTICALS CO (JP) | 2022-01-05 | — | — | EP | disclosed |
| US-20210171565-A1 | STING MODULATOR COMPOUNDS, AND METHODS OF MAKING AND USING | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11542293-B2 | Sting modulator compounds, and methods of making and using | STING1, CGAS, MAVS | NAE1 1571/4885UBA3 2354/4885SAE1 2353/4885 |
| US-20240209017-A1 | STING MODULATOR COMPOUNDS, AND METHODS OF MAKING AND USING | STING1, CGAS, MAVS | NAE1 1571/4885UBA3 2354/4885SAE1 2353/4885 |
| US-12054512-B2 | Sting modulator compounds, and methods of making and using | STING1, CGAS, MAVS | NAE1 1571/4885UBA3 2354/4885SAE1 2353/4885 |
| US-20210171565-A1 | STING MODULATOR COMPOUNDS, AND METHODS OF MAKING AND USING | STING1, CGAS, MAVS | NAE1 1571/4885UBA3 2354/4885SAE1 2353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.