Stearic Acid

Stearic Acid

SCHEMBL2345646

CCCCCCCCCCCCCCCCCC(=O)O.OCCCCCCCCCCCCCCCCCCO

nearest known ligand 0.81

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Known targets — ChEMBL curated mechanism

rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 8/20 0.81
PPARG P37231 7/20 0.81
PPARD Q03181 7/20 0.81
PPARA Q07869 7/20 0.81
HDAC11 Q96DB2 5/20 0.81
TSHR P16473 4/20 0.81
PTPN1 P18031 3/20 0.81
FABP4 P15090 3/20 0.81
ALDH1A1 P00352 2/20 0.81
TLR2 O60603 2/20 0.81
TDP1 Q9NUW8 2/20 0.81
FFAR1 O14842 2/20 0.81
FFAR4 Q5NUL3 2/20 0.81
KMT2A Q03164 2/20 0.81
ALOX15 P16050 2/20 0.81
HSD17B10 Q99714 2/20 0.81
SLC22A6 Q4U2R8 1/20 0.81
SLC22A8 Q8TCC7 1/20 0.81
MEN1 O00255 1/20 0.81
ESR1 P03372 1/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cetostearyl Alcohol SCHEMBL5499260 1.00 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL1490308 1.00 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11
Decanoic Acid SCHEMBL17219627 1.00 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11
Tridecan-1-Ol SCHEMBL15123819 1.00 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11
Cetyl Alcohol SCHEMBL21647227 1.00 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11
Behenic Acid SCHEMBL23148258 1.00 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11
Tridecan-1-Ol SCHEMBL15123811 1.00 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11
Nonanol SCHEMBL15124104 1.00 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11
Palmitic Acid SCHEMBL1490390 1.00 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11
Octanoic Acid SCHEMBL11429630 1.00 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9034553-B2 Method of foil transfer employing foil transferring face forming toner and image forming method Konica Minolta Business Technologes, Inc. (JP) 2015-05-19 US disclosed
CN-103961268-A Clean composition with lyotropic liquid crystal structure SUZHOU ELECO CHEMICAL INDUSTRY CO LTD 2014-08-06 CN disclosed
CN-103932905-A Composition inducing to form lyotropic liquid crystal structure SUZHOU ELECO CHEMICAL INDUSTRY CO LTD 2014-07-23 CN disclosed
US-8273518-B2 Electrophotographic toner, electrophotographic developer and production method of electrophotographic toner KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-09-25 US disclosed
US-20110229819-A1 METHOD OF FOIL TRANSFER EMPLOYING FOIL TRANSFERRING FACE FORMING TONER AND IMAGE FORMING METHOD KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-09-22 US disclosed
US-20110207045-A1 TONER FOR ELECTROSTATIC LATENT IMAGE DEVELOPMENT AND PRODUCTION METHOD THEREOF KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-08-25 US disclosed
US-20090208863-A1 ELECTROPHOTOGRAPHIC TONER, ELECTROPHOTOGRAPHIC DEVELOPER AND PRODUCTION METHOD OF ELECTROPHOTOGRAPHIC TONER KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-08-20 US disclosed