SCHEMBL2345932

SCHEMBL2345932

CCCC[Sn+2]CCC.C[O-].C[O-]

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.33
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30
ANPEP P15144 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL55393 0.94 TSHR (0.40) TSHRLMNATHRBCES2CES1
SCHEMBL2341364 0.88 TSHR (0.32) TSHRLMNATHRB
SCHEMBL3886109 0.84 TSHR (0.38) TSHRLMNATHRBCES2CES1
SCHEMBL6121770 0.83 TSHR (0.43) TSHRLMNATHRBANPEP
Iodide SCHEMBL1172044 0.83 TSHR (0.43) TSHRLMNATHRBANPEP
Hydrochloric Acid SCHEMBL98192 0.83 TSHR (0.43) TSHRLMNATHRBANPEP
SCHEMBL152801 0.83 TSHR (0.43) TSHRLMNATHRBANPEP
SCHEMBL15122 0.83 TSHR (0.43) TSHRLMNATHRBANPEP
Fluoride Ion SCHEMBL839652 0.83 TSHR (0.43) TSHRLMNATHRBANPEP
Water SCHEMBL439121 0.83 TSHR (0.43) TSHRLMNATHRBANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1640357-B1 METHOD FOR PRODUCING AROMATIC CARBONATE ASAHI KASEI CHEMICALS CORP (JP) 2011-08-31 EP disclosed
US-7652122-B2 Method for producing an aromatic carbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-01-26 US disclosed
US-20070055042-A1 Method for producing an aromatic carbonate ASAHI KASEI KABUSHIKI KAISHA (JP) 2007-03-08 US disclosed
EP-1640357-A1 METHOD FOR PRODUCING AROMATIC CARBONATE Asahi Kasei Chemicals Corporation (JP) 2006-03-29 EP disclosed