Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18528453 | 0.93 | TSHR (0.38) | TSHRLMNATHRBANPEPALDH1A1 | |
| Fluoride Ion SCHEMBL839652 | 0.92 | TSHR (0.43) | TSHRLMNATHRBANPEPALDH1A1 | |
| SCHEMBL15122 | 0.92 | TSHR (0.43) | TSHRLMNATHRBANPEPALDH1A1 | |
| Hydrogen Sulfide SCHEMBL9252049 | 0.92 | TSHR (0.43) | TSHRLMNATHRBANPEPALDH1A1 | |
| Iodide SCHEMBL1172044 | 0.92 | TSHR (0.43) | TSHRLMNATHRBANPEPALDH1A1 | |
| Water SCHEMBL439121 | 0.92 | TSHR (0.43) | TSHRLMNATHRBANPEPALDH1A1 | |
| SCHEMBL152801 | 0.92 | TSHR (0.43) | TSHRLMNATHRBANPEPALDH1A1 | |
| SCHEMBL6121770 | 0.92 | TSHR (0.43) | TSHRLMNATHRBANPEPALDH1A1 | |
| Bromide SCHEMBL154033 | 0.92 | TSHR (0.43) | TSHRLMNATHRBANPEPALDH1A1 | |
| Cyclohexane SCHEMBL9235142 | 0.90 | CYP1A2 (0.36) | TSHRLMNATHRBANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 10786 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122037116-A | Combined polyether, polyurethane composition, polyurethane foam, preparation method of polyurethane foam and refrigeration equipment | TCL家用电器（合肥）有限公司 | 2026-05-15 | — | — | CN | claimed |
| US-12559453-B2 | Sulfonic acid-modified polyisocyanate and preparation method therefor | WANHUA CHEMICAL GROUP CO., LTD. (CN) | 2026-02-24 | — | — | US | claimed |
| US-20260008903-A1 | POLYTHIOL COMPOSITION AND USE THEREOF | Efirm New Material Co., Ltd. (CN) | 2026-01-08 | — | — | US | claimed |
| EP-4144780-B1 | SULFONIC ACID-MODIFIED POLYISOCYANATE AND PREPARATION METHOD THEREFOR | WANHUA CHEMICAL GROUP CO LTD (CN) | 2025-12-24 | — | — | EP | claimed |
| EP-4663686-A1 | ELECTRICALLY DEBONDABLE SILYL MODIFIED POLYMER-BASED ADHESIVE | Henkel AG & Co. KGaA (DE) | 2025-12-17 | — | — | EP | claimed |
| US-12468084-B2 | Systems and methods of making polymeric optical layers for optical layering | FACEBOOK TECHNOLOGIES, LLC (US) | 2025-11-11 | — | — | US | claimed |
| US-20250270202-A1 | SUBSTITUTED 4-AMINOISOINDOLINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2025-08-28 | — | — | US | claimed |
| US-12304991-B2 | Photochromic article | TRANSITIONS OPTICAL, LTD. (IE) | 2025-05-20 | — | — | US | claimed |
| CN-119930972-A | Polyurethane forming system and composite material formed by same | 万华化学（北京）有限公司 | 2025-05-06 | — | — | CN | claimed |
| EP-4545524-A1 | SUBSTITUTED 4-AMINOISOINDOLINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2025-04-30 | — | — | EP | claimed |
| US-4663405-A | ADDITION POLYMERIZATION COORDINATION CATALYSTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1987-05-05 | — | — | US | claimed |
| US-4601917-A | CHEMICAL VAPOR DEPOSITION | M&T CHEMICALS INC. (US) | 1986-07-22 | — | — | US | claimed |
| EP-0186481-A2 | Improved chemical vapor deposition method of producing fluorine-doped tin oxide coatings | M & T CHEMICALS, INC. (US) | 1986-07-02 | — | — | EP | claimed |
| EP-0038971-B1 | SHAPED BODIES OF PLASTICS CONTAINING ANTI-FOULING AGENTS ON THE BASIS OF TIN COMPOUNDS, AND THEIR USE AS SEALING WEBS | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1985-11-27 | — | — | EP | claimed |
| US-4499145-A | METAL FOIL, SILANE-MODIFIED POLYETHYLENE, PAPER OR GLASS CONTAININNG EPOXY AND DIELECTRIC; MOISTURE AND HEAT RESISTANCE | SUMITOMO BAKELITE COMPANY LIMITED (JP) | 1985-02-12 | — | — | US | claimed |
| US-4473702-A | CATALYTIC ESTER INTERCHANGE BETWEEN DIALKYL ESTER OF DICARBOXYLIC ACID AND ALLYL ALCOHOL | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-09-25 | — | — | US | claimed |
| EP-0029362-B1 | PRODUCTION OF A DIALLYL ESTER OF AN AROMATIC DICARBOXYLIC ACID | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-09-07 | — | — | EP | claimed |
| EP-0029362-A1 | Production of a diallyl ester of an aromatic dicarboxylic acid | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1981-05-27 | — | — | EP | claimed |
| US-4061844-A | AMINOALKYL ACRYLATE COPOLYMER, SILICON OR TIN COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-12-06 | — | — | US | claimed |
| US-4028337-A | REACTION WITH ORGANO-TIN COMPOUNDS, SOLVENT EXTRACTION | BELL TELEPHONE LABORATORIES, INCORPORATED (US) | 1977-06-07 | — | — | US | claimed |