Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.50 |
| ▸ | MEN1 | O00255 | 8/20 | 0.50 |
| ▸ | USP2 | O75604 | 7/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 7/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21996572 | 0.88 | GBA1 (0.55) | GBA1KMT2AMEN1USP2CYP1A2 | |
| SCHEMBL30162860 | 0.88 | GBA1 (0.55) | GBA1KMT2AMEN1USP2CYP1A2 | |
| SCHEMBL29840025 | 0.87 | GBA1 (0.70) | GBA1KMT2AMEN1USP2CYP1A2 | |
| SCHEMBL21996554 | 0.87 | GBA1 (0.70) | GBA1KMT2AMEN1USP2CYP1A2 | |
| SCHEMBL30867198 | 0.80 | GBA1 (0.49) | GBA1KMT2AMEN1USP2CYP1A2 | |
| SCHEMBL27319878 | 0.80 | GBA1 (0.49) | GBA1KMT2AMEN1USP2CYP1A2 | |
| SCHEMBL21753171 | 0.79 | GBA1 (0.49) | GBA1KMT2AMEN1USP2CYP1A2 | |
| SCHEMBL31297701 | 0.79 | GBA1 (0.49) | GBA1KMT2AMEN1USP2CYP1A2 | |
| SCHEMBL21996567 | 0.77 | GBA1 (0.46) | GBA1KMT2AMEN1USP2CYP1A2 | |
| SCHEMBL23459664 | 0.77 | GBA1 (0.46) | GBA1KMT2AMEN1USP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113849-A1 | HER2+ CANCER TREATMENT WITH POPULATIONS OF NATURAL KILLER CELLS COMPRISING A CLEAVAGE RESISTANT CD16 | CELULARITY INC. (US) | 2021-06-10 | — | — | WO | disclosed |