Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 11/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 11/20 | 0.52 |
| ▸ | MEN1 | O00255 | 10/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 10/20 | 0.52 |
| ▸ | USP2 | O75604 | 10/20 | 0.52 |
| ▸ | LMNA | P02545 | 9/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21996572 | 1.00 | GBA1 (0.55) | GBA1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL21996554 | 0.89 | GBA1 (0.70) | GBA1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29840025 | 0.89 | GBA1 (0.70) | GBA1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL23459690 | 0.88 | GBA1 (0.53) | GBA1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL21996558 | 0.87 | GBA1 (0.58) | GBA1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30162953 | 0.87 | GBA1 (0.58) | GBA1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL21996597 | 0.87 | GBA1 (0.58) | GBA1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30162649 | 0.87 | GBA1 (0.58) | GBA1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30867198 | 0.80 | GBA1 (0.49) | GBA1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27319878 | 0.80 | GBA1 (0.49) | GBA1KMT2ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023010123-A1 | PLACENTA-DERVIED NK CELLS AS A SENOLYTIC FOR THERAPEUTIC AND OTHER USES | CELULARITY INC. (US) | 2023-02-02 | — | — | WO | disclosed |
| WO-2023278628-A1 | HUMAN PLACENTAL HEMATOPOIETIC STEM CELL DERIVED NATURAL KILLER CELLS IN ACUTE MYELOID LEUKEMIA (AML) REMISSION WITH MINIMAL RESIDUAL DISEASE (MRD) OR RELAPSED/REFRACTORY AML | CELULARITY INC. (US) | 2023-01-05 | — | — | WO | disclosed |