SCHEMBL23462120

SCHEMBL23462120

CCC(O)=S.CCC(O)=S.[N-]=[N+]=Nc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGS2 P35354 4/20 0.57
▸ CYP2D6 P10635 1/20 0.40
▸ CYP2C19 P33261 1/20 0.40
▸ TP53 P04637 1/20 0.39
▸ NOS3 P29474 3/20 0.38
▸ NOS1 P29475 3/20 0.38
▸ SCN1A P35498 1/20 0.37
▸ SCN2A Q99250 1/20 0.37
▸ SCN3A Q9NY46 1/20 0.37
▸ SMO Q99835 1/20 0.36
▸ ATM Q13315 1/20 0.35
▸ RIPK1 Q13546 1/20 0.35
▸ CA1 P00915 1/20 0.35
▸ CA2 P00918 1/20 0.35
▸ CA5A P35218 1/20 0.35
▸ CA9 Q16790 1/20 0.35
▸ CA5B Q9Y2D0 1/20 0.35
▸ NOS2 P35228 1/20 0.34
▸ SIGMAR1 Q99720 1/20 0.34
▸ NOX1 Q9Y5S8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propane SCHEMBL23922782 0.86 PTGS2 (0.56) PTGS2CYP2D6CYP2C19TP53NOS3
Succinimide SCHEMBL29036429 0.85 PTGS2 (0.45) PTGS2CYP2D6CYP2C19TP53SCN1A
SCHEMBL27718958 0.83 PTGS2 (0.55) PTGS2CYP2D6CYP2C19TP53SCN1A
Benzene SCHEMBL28456073 0.81 PTGS2 (0.48) PTGS2CYP2D6CYP2C19TP53SMO
SCHEMBL13475909 0.81 — —
Phosphine SCHEMBL29065184 0.79 PTGS2 (0.47) PTGS2CYP2D6CYP2C19TP53SMO
Fluoride SCHEMBL28295332 0.79 PTGS2 (0.47) PTGS2CYP2D6CYP2C19TP53SMO
SCHEMBL17289458 0.79 PTGS2 (0.47) PTGS2CYP2D6CYP2C19TP53SMO
Fluoride SCHEMBL27800819 0.79 PTGS2 (0.47) PTGS2CYP2D6CYP2C19TP53SMO
Acetic Acid SCHEMBL29006939 0.78 PTGS2 (0.49) PTGS2CYP2D6CYP2C19TP53NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111902148-B Compositions and methods for treating muscular atrophy and tonic muscular dystrophy 艾维迪提生物科学公司 2024-07-05 — — CN disclosed
CN-118267396-A Nucleic acid-polypeptide compositions and uses thereof 艾维迪提生物科学公司 2024-07-02 — — CN disclosed
CN-118265544-A Compositions and methods for treating facial shoulder brachial muscular dystrophy 艾维迪提生物科学公司 2024-06-28 — — CN disclosed
EP-4374172-A2 COMPOSITIONS AND METHODS FOR DETECTION OF BREAST CANCER Mercy Bioanalytics, Inc. (US) 2024-05-29 — — EP disclosed
CN-116063505-B Anti-GAL 3 antibodies and uses thereof 真和制药有限公司 2024-05-03 — — CN disclosed
CN-117940557-A Method for preparing modified tumor-infiltrating lymphocytes and application of modified tumor-infiltrating lymphocytes in adoptive cell therapy 艾欧凡斯生物治疗公司 2024-04-26 — — CN disclosed
CN-117916269-A Method for preventing aggregation of proteins 真和制药有限公司 2024-04-19 — — CN disclosed
CN-109715805-B Nucleic acid-polypeptide compositions and uses thereof 艾维迪提生物科学公司 2024-01-05 — — CN disclosed
US-20230183359-A1 WNT SIGNALING AGONIST MOLECULES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2023-06-15 — — US disclosed
WO-2023091618-A1 COMPOSITIONS AND METHODS FOR DETECTION OF OVARIAN CANCER MERCY BIOANALYTICS, INC. (US) 2023-05-25 — — WO disclosed
WO-2021146659-A1 COMPOSITIONS AND METHODS FOR DETECTION OF OVARIAN CANCER MERCY BIOANALYTICS, INC. (US) 2021-07-22 — — WO disclosed
WO-2021113290-A1 NUCLEIC ACID LINKED IMMUNE-SANDWICH ASSAY (NULISA) ALAMAR BIOSCIENCES, INC. (US) 2021-06-10 — — WO disclosed
CN-112040959-A Treatment of cancer by blocking the interaction of VISTA and its binding partners 真和制药有限公司 2020-12-04 — — CN disclosed
CN-112004547-A IL-15 conjugates and uses thereof 新索思股份有限公司 2020-11-27 — — CN disclosed
CN-111902148-A Compositions and methods for treating muscular atrophy and myotonic dystrophy 艾维迪提生物科学公司 2020-11-06 — — CN disclosed
CN-111655268-A Nucleic acid-polypeptide compositions and uses thereof 艾维迪提生物科学公司 2020-09-11 — — CN disclosed
CN-111587124-A ROR1 antibody immunoconjugates 维洛斯生物股份有限公司 2020-08-25 — — CN disclosed
CN-111225958-A Conductive antifouling coating composition 哈佛大学校长及研究员协会 2020-06-02 — — CN disclosed
CN-111194322-A Cytokine conjugates for the treatment of proliferative and infectious diseases 辛索克斯公司 2020-05-22 — — CN disclosed
CN-111183149-A Cytokine conjugates for the treatment of autoimmune diseases 辛索克斯公司 2020-05-19 — — CN disclosed
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