Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 4/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535248 | 0.84 | LMNA (0.55) | LMNAMAPTMAPK1PRKCAPRKCE | |
| SCHEMBL155921 | 0.79 | LMNA (0.63) | LMNAMAPTMAPK1CAMK2APRKCA | |
| Hydrochloric Acid SCHEMBL6385125 | 0.77 | LMNA (0.61) | LMNAMAPTMAPK1CAMK2APRKCA | |
| SCHEMBL4334239 | 0.76 | MGAM (0.35) | LMNATSHRFAAHCNR1CNR2 | |
| SCHEMBL2169906 | 0.74 | LMNA (0.32) | LMNA | |
| SCHEMBL15319453 | 0.73 | LMNA (0.42) | LMNAMAPTMAPK1CAMK2APRKCA | |
| SCHEMBL19588562 | 0.73 | LMNA (0.42) | LMNAMAPTMAPK1CAMK2APRKCA | |
| SCHEMBL23754243 | 0.73 | LMNA (0.42) | LMNAMAPTMAPK1CAMK2APRKCA | |
| SCHEMBL3130321 | 0.73 | LMNA (0.42) | LMNAMAPTMAPK1CAMK2APRKCA | |
| SCHEMBL6741083 | 0.73 | LMNA (0.47) | LMNAMAPTMAPK1CAMK2APRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113665-A1 | RAPAMYCIN ANALOGS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2021-06-10 | — | — | WO | disclosed |