⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL234662 | 1.00 | — | — | |
| SCHEMBL507249 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL578996 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL578995 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL2253880 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL4018035 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL4486116 | 0.92 | — | — | |
| Propylamine SCHEMBL18917424 | 0.80 | ALDH1A1 (0.35) | — | |
| SCHEMBL12681801 | 0.78 | — | — | |
| SCHEMBL16992975 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 867 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119600-A | SOS1 inhibitors and uses thereof | 治纳辅医药科技有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-116410106-A | Benzamide HBV capsid protein inhibitor and preparation method and application thereof | 潍坊医学院 | 2023-07-11 | — | — | CN | claimed |
| WO-2022143652-A1 | TRANSAMINASE AND APPLICATION THEREOF IN PREPARING OPTICALLY PURE CHIRAL AMINE | 上海合全药物研发有限公司 | 2022-07-07 | — | — | WO | claimed |
| CN-114057745-A | Preparation method and application of triazolo [1,5-a ] pyrazine | 江苏恒瑞医药股份有限公司 | 2022-02-18 | — | — | CN | claimed |
| CN-113881647-A | Transaminase and application thereof in preparation of optically pure chiral amine | 上海合全药物研发有限公司 | 2022-01-04 | — | — | CN | claimed |
| CN-108123175-B | Synthesis method of amide compound, amide compound and non-aqueous electrolyte | 微宏动力系统（湖州）有限公司 | 2020-05-22 | — | — | CN | claimed |
| EP-2427456-B1 | ISOXAZOLE-PYRIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2020-02-05 | — | — | EP | claimed |
| US-10155770-B2 | Substituted pyrazolopyrimidines and method of use | ABBVIE INC. (US) | 2018-12-18 | — | — | US | claimed |
| US-9879293-B2 | Enzymatic transamination of cyclopamine analogs | INFINITY PHARMACEUTICALS, INC. (US) | 2018-01-30 | — | — | US | claimed |
| EP-2763990-B1 | PYRROLOPYRAZINE KINASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2017-02-22 | — | — | EP | claimed |
| US-20060247289-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INCORPORATED | 2006-11-02 | — | — | US | claimed |
| EP-0931082-A4 | NODULISPORIC ACID DERIVATIVES | MERCK & CO INC (US) | 1999-11-17 | — | — | EP | claimed |
| US-5986135-A | CHEMICAL INTERMEDIATES | AMERICAN CYANAMID COMPANY (US) | 1999-11-16 | — | — | US | claimed |
| EP-0931082-A1 | NODULISPORIC ACID DERIVATIVES | Merck & Co., Inc. (a New Jersey corp.) (US) | 1999-07-28 | — | — | EP | claimed |
| WO-1998012196-A1 | NODULISPORIC ACID DERIVATIVES | MERCK & CO., INC. (US) | 1998-03-26 | — | — | WO | claimed |
| EP-0323637-B1 | L(-) 2,6-DIFLUOROBENZOIC-N-(1,1,1-TRIFLUORO-PROP-2-YL)AMIDE | BAYER AG (DE) | 1992-12-16 | — | — | EP | claimed |
| EP-0323637-A1 | L(-) 2,6-difluorobenzoic-N-(1,1,1-trifluoro-prop-2-yl)amide | BAYER AG (DE) | 1989-07-12 | — | — | EP | claimed |
| US-4767757-A | Acyloxythiophene-carboxamide fungicides, compositions and use | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-30 | — | — | US | claimed |
| EP-0241735-A2 | Acyloxythiophene carbon amide | BAYER AG (DE) | 1987-10-21 | — | — | EP | claimed |
| US-4491671-A | Process for the preparation of N-substituted imido-dicarboxylic acid diaryl esters | BAYER AKTIENGESELLSCHAFT (DE) | 1985-01-01 | — | — | US | claimed |