Sulfisoxazole

Sulfisoxazole

SCHEMBL23467

Cc1noc(NS(=O)(=O)c2ccc(N)cc2)c1C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

folP

The experimentally established mechanism targets of Sulfisoxazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
EDNRA P25101 13/20 1.00
EDNRB P24530 9/20 1.00
MEN1 O00255 1/20 1.00
CYP2C9 P11712 1/20 1.00
TSHR P16473 1/20 1.00
CYP2C19 P33261 1/20 1.00
ADRA1A P35348 1/20 1.00
KMT2A Q03164 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfisoxazole SCHEMBL788644 1.00 EDNRA (1.00) EDNRAEDNRBMEN1CYP2C9TSHR
Sulfisoxazole SCHEMBL5917298 0.98 EDNRA (0.97) EDNRAEDNRBMEN1CYP2C9TSHR
Sulfisoxazole SCHEMBL2200933 0.98 EDNRA (0.97) EDNRAEDNRBMEN1CYP2C9TSHR
Sulfisoxazole SCHEMBL5959142 0.96 EDNRA (0.92) EDNRAEDNRBMEN1CYP2C9TSHR
Sulfisoxazole SCHEMBL16097888 0.94 EDNRA (0.89) EDNRAEDNRBMEN1CYP2C9TSHR
Sulfisoxazole SCHEMBL3221114 0.91 EDNRA (0.82) EDNRAEDNRBMEN1CYP2C9TSHR
Sulfisoxazole SCHEMBL20770061 0.90 EDNRA (0.81) EDNRAEDNRBMEN1CYP2C9TSHR
Sulfisoxazole SCHEMBL4973236 0.90 EDNRA (0.81) EDNRAEDNRBMEN1CYP2C9TSHR
Sulfisoxazole SCHEMBL28264710 0.90 EDNRA (0.81) EDNRAEDNRBMEN1CYP2C9TSHR
Sulfisoxazole SCHEMBL887764 0.89 EDNRA (0.79) EDNRAEDNRBMEN1CYP2C9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 23090 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4739326-A2 PRODUCTION & SECRETION OF AUXIN-LIKE MOLECULES IN BACTERIA SNIPR Biome ApS (DK) 2026-05-13 EP claimed
CN-122028915-A Frontotemporal lobar degenerative disease therapeutic agent and therapeutic composition 凯制药股份有限公司 2026-05-12 CN claimed
US-20260115234-A1 PRODUCTION & SECRETION OF AUXIN-LIKE MOLECULES IN BACTERIA SNIPR BIOME APS (DK) 2026-04-30 US claimed
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US claimed
EP-4724049-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF Catalent Ontario Limited (CA) 2026-04-15 EP claimed
US-20260091089-A1 Pyocyanine Demethylases and related Phenazine Degrading Agents Compositions, Methods and Systems for Interfering with Viability of Bacteria CALIFORNIA INST OF TECHN (US) 2026-04-02 US claimed
US-20260091119-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF GLIOMA CELLIS AG (CH) 2026-04-02 US claimed
US-20260076872-A1 POLYMER VIALS WITH SUBSTANTIALLY FLAT BOTTOMS AND INJECTION STRETCH BLOW MOLDING METHODS FOR MAKING THE SAME SIO2 MEDICAL PRODUCTS LLC (US) 2026-03-19 US claimed
US-12576124-B2 Formulation of a conjugate of a tubulysin analog to a cell-binding molecule HANGZHOU DAC BIOTECH CO., LTD (CN) 2026-03-17 US claimed
EP-4694929-A1 METHODS FOR TREATING CORNEAL INJURIES Lin, Sung-Jan (TW) 2026-02-18 EP claimed
US-4315931-A MICROBIOCIDES, INFECTIOUS DISEASES BASF AKTIENGESELLSCHAFT (DE) 1982-02-16 US claimed
US-4235236-A Device for dispensing drug by combined diffusional and osmotic operations ALZA CORPORATION (US) 1980-11-25 US claimed
US-4186184-A Selective administration of drug with ocular therapeutic system ALZA CORPORATION (US) 1980-01-29 US claimed
US-4169763-A OF A CORYNEBACTERIA RESISTANT TO ASPARTIC ACID ANALOGS AND SULFA DRUGS KYOWA HAKKO KOGYO CO., LTD. (JP) 1979-10-02 US claimed
US-4133879-A Process for producing stable solutions of a sulphonamide and a potentiator AKTIESELSKABET ROSCO (DK) 1979-01-09 US claimed
US-4016251-A Vaginal drug dispensing device ALZA CORPORATION (US) 1977-04-05 US claimed
US-4014335-A Ocular drug delivery device ALZA CORPORATION (US) 1977-03-29 US claimed
US-3996356-A ANTIBACTERIAL HOFFMANN-LA ROCHE INC. (US) 1976-12-07 US claimed
US-3963532-A IRON, CHROMIUM, ALUMINUM, NIOBIUM E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-06-15 US claimed
US-3962436-A Pharmaceutical compositions having controlled rate of gastro-intestinal absorption SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-06-08 US claimed