Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.33 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29770896 | 1.00 | KDM4C (0.40) | KDM4CCNR2GRM2POLBKMT2A | |
| SCHEMBL5443607 | 0.80 | KDM4C (0.39) | KDM4CCNR2GRM2POLBKMT2A | |
| SCHEMBL23467063 | 0.77 | GRIN1 (0.35) | KDM4CPOLBKMT2A | |
| SCHEMBL23467054 | 0.77 | PGR (0.41) | KDM4CCNR2CNR1ACHE | |
| SCHEMBL29771070 | 0.77 | GRIN1 (0.35) | KDM4CPOLBKMT2A | |
| SCHEMBL29770916 | 0.77 | PGR (0.41) | KDM4CCNR2CNR1ACHE | |
| SCHEMBL5307216 | 0.76 | CNR2 (0.48) | KDM4CCNR2POLBKMT2ACNR1 | |
| SCHEMBL23467072 | 0.75 | ESR1 (0.38) | CNR2CNR1KDM2B | |
| SCHEMBL5437713 | 0.75 | CNR1 (0.40) | KDM4CCNR2GRM2KMT2ACNR1 | |
| SCHEMBL29770962 | 0.75 | ESR1 (0.38) | CNR2CNR1KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12479836-B2 | Sphingosine-1-phosphate receptor agonist, preparation method therefor, and pharmaceutical composition containing same as active ingredient | LG CHEM, LTD. (KR) | 2025-11-25 | — | — | US | disclosed |
| EP-4050010-B1 | SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE AGENT | LG CHEMICAL LTD (KR) | 2023-10-18 | — | — | EP | disclosed |
| US-20230047472-A1 | SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | LG CHEM, LTD. (KR) | 2023-02-16 | — | — | US | disclosed |
| EP-4050010-A1 | SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE AGENT | LG Chem, Ltd. (KR) | 2022-08-31 | — | — | EP | disclosed |
| CN-114761401-A | Sphingosine-1-phosphate receptor agonists, method for the preparation thereof and pharmaceutical compositions containing the same as active ingredient | 株式会社LG化学 | 2022-07-15 | — | — | CN | disclosed |
| WO-2021112461-A1 | SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE AGENT | 주식회사 엘지화학 | 2021-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12479836-B2 | Sphingosine-1-phosphate receptor agonist, preparation method therefor, and pharmaceutical composition containing same as active ingredient | S1PR1, S1PR2, S1PR4 | KDM4C 3719/4885CNR2 40/4885GRM2 971/4885 |
| US-20230047472-A1 | SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | S1PR1, S1PR2, S1PR4 | KDM4C 3719/4885CNR2 40/4885GRM2 971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.