SCHEMBL234692

SCHEMBL234692

CCCCN(CC)CCN[SiH](NC)NC

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 1/20 0.36
KDM4C Q9H3R0 1/20 0.36
ALOX15 P16050 1/20 0.35
ALDH1A1 P00352 1/20 0.34
KCNH2 Q12809 4/20 0.33
HTR1D P28221 1/20 0.33
HTR1B P28222 1/20 0.33
MCL1 Q07820 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL235928 0.86 CHEK1 (0.33) ALDH1A1
SCHEMBL235318 0.79
SCHEMBL234855 0.78 S1PR2 (0.35) KDM5AKDM4C
SCHEMBL12478475 0.77 EPHX1 (0.44) KDM5AKDM4CALOX15ALDH1A1KCNH2
SCHEMBL217114 0.73 KCNH2 (0.47) KDM5AKDM4CKCNH2HTR1DHTR1B
SCHEMBL234948 0.72 KDM5A (0.38) KDM5AKDM4CALDH1A1KCNH2HTR1D
SCHEMBL13267574 0.71 TSHR (0.50) KDM5AKDM4CALOX15ALDH1A1KCNH2
SCHEMBL236718 0.71
SCHEMBL234938 0.71 KDM5A (0.36) KDM5AKDM4CKCNH2
SCHEMBL20431090 0.71 EPHX1 (0.48) KDM5AKDM4CALDH1A1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360190-B1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO LTD (JP) 2015-10-14 EP disclosed
US-8426537-B2 Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO., LTD. (JP) 2013-04-23 US disclosed
US-20120004378-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO., LTD (JP) 2012-01-05 US disclosed
EP-2360190-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME Toho Titanium CO., LTD. (JP) 2011-08-24 EP disclosed