SCHEMBL235928

SCHEMBL235928

CCN(CC)CCN[SiH](NC)NC

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.33
PIM1 P11309 1/20 0.33
IDO1 P14902 1/20 0.33
LTK P29376 1/20 0.33
LIMK1 P53667 1/20 0.33
CLK4 Q9HAZ1 1/20 0.33
SIGMAR1 Q99720 2/20 0.31
KMT2A Q03164 1/20 0.30
SLC22A2 O15244 1/20 0.30
SLC22A1 O15245 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30
ACHE P22303 1/20 0.30
MAPK1 P28482 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL233293 0.86
SCHEMBL234692 0.86 KDM5A (0.36) ALDH1A1
SCHEMBL235318 0.84
SCHEMBL236718 0.79
SCHEMBL233424 0.75 PRMT3 (0.50) ALDH1A1TSHRCYP2C19
SCHEMBL233598 0.74
SCHEMBL40090 0.71
SCHEMBL234855 0.70 S1PR2 (0.35)
Hydrochloric Acid SCHEMBL11539426 0.69 PRMT3 (0.48) CHEK1PIM1IDO1LTKLIMK1
Ammonia Solution, Strong SCHEMBL19410301 0.69 PRMT3 (0.48) CHEK1PIM1IDO1LTKLIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360190-B1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO LTD (JP) 2015-10-14 EP disclosed
US-8426537-B2 Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO., LTD. (JP) 2013-04-23 US disclosed
US-20120004378-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO., LTD (JP) 2012-01-05 US disclosed
EP-2360190-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME Toho Titanium CO., LTD. (JP) 2011-08-24 EP disclosed