Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 3/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20459229 | 0.81 | CRBN (0.43) | DDB1CRBNCYP19A1 | |
| SCHEMBL22199360 | 0.79 | AKR1B1 (0.34) | CYP19A1 | |
| SCHEMBL21281328 | 0.77 | CYP19A1 (0.35) | DDB1CRBNCYP19A1 | |
| SCHEMBL19310101 | 0.76 | DDB1 (0.31) | DDB1CRBN | |
| SCHEMBL19309922 | 0.71 | AKR1B1 (0.33) | — | |
| SCHEMBL21927072 | 0.68 | AKR1B1 (0.32) | CYP19A1 | |
| SCHEMBL22686890 | 0.65 | TNF (0.36) | DDB1CRBN | |
| SCHEMBL22199340 | 0.65 | — | — | |
| SCHEMBL21925221 | 0.65 | — | — | |
| SCHEMBL19541433 | 0.64 | DDB1 (0.33) | DDB1CRBNCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3527210-B1 | COMBINED COMPOSITION COMPRISING A BENZOHETEROCYCLIC COMPOUND AND AN ANDROGEN RECEPTOR PATHWAY MODULATOR AND USES THEREOF | KANGPU BIOPHARMACEUTICALS LTD (CN) | 2021-06-09 | — | — | EP | disclosed |