Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | CYP11A1 | P05108 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864786 | 0.81 | CRBN (0.39) | CYP19A1CYP3A4CYP17A1CYP11A1TBXAS1 | |
| SCHEMBL21927072 | 0.78 | AKR1B1 (0.32) | CYP19A1 | |
| SCHEMBL19309977 | 0.78 | AKR1B1 (0.32) | CYP19A1 | |
| SCHEMBL19541433 | 0.77 | DDB1 (0.33) | CYP19A1DDB1CRBN | |
| SCHEMBL23470170 | 0.77 | DDB1 (0.33) | CYP19A1DDB1CRBN | |
| SCHEMBL19309922 | 0.76 | AKR1B1 (0.33) | — | |
| SCHEMBL19310041 | 0.72 | — | — | |
| SCHEMBL22199340 | 0.71 | — | — | |
| SCHEMBL21925221 | 0.71 | — | — | |
| SCHEMBL21281321 | 0.70 | CRBN (0.50) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3527210-A1 | COMPOSITION, APPLICATION THEREOF AND TREATMENT METHOD | Kangpu Biopharmaceuticals, Ltd. (CN) | 2019-08-21 | — | — | EP | disclosed |