SCHEMBL234710

SCHEMBL234710

COC(=O)c1ccccc1C(=O)OC(C)C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.57
LMNA P02545 2/20 0.57
NPC1 O15118 2/20 0.56
ALDH1A1 P00352 6/20 0.55
HSD17B10 Q99714 2/20 0.55
CFTR P13569 1/20 0.55
KDM4E B2RXH2 4/20 0.53
POLB P06746 1/20 0.53
ATM Q13315 1/20 0.53
CA1 P00915 4/20 0.50
CA2 P00918 4/20 0.50
CA9 Q16790 4/20 0.50
CA12 O43570 3/20 0.50
CA7 P43166 3/20 0.50
CA14 Q9ULX7 3/20 0.50
PDCD1 Q15116 1/20 0.50
CD274 Q9NZQ7 1/20 0.50
CA5A P35218 1/20 0.49
MAPT P10636 1/20 0.49
ALOX15 P16050 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL137907 0.92 NPC1 (0.62) TSHRLMNANPC1ALDH1A1HSD17B10
SCHEMBL22164112 0.86 NPC1 (0.57) TSHRLMNANPC1ALDH1A1HSD17B10
Dimethyl Phthalate SCHEMBL790124 0.85 TSHR (0.74) TSHRLMNAALDH1A1HSD17B10CFTR
Dimethyl Phthalate SCHEMBL34630 0.85 TSHR (0.74) TSHRLMNAALDH1A1HSD17B10CFTR
Dimethyl Phthalate SCHEMBL29669976 0.85 TSHR (0.74) TSHRLMNAALDH1A1HSD17B10CFTR
Dimethyl Phthalate SCHEMBL29500970 0.85 TSHR (0.74) TSHRLMNAALDH1A1HSD17B10CFTR
SCHEMBL28595770 0.85 NPC1 (0.53) TSHRLMNANPC1ALDH1A1HSD17B10
SCHEMBL12413026 0.85 KDM4E (0.55) TSHRLMNAALDH1A1HSD17B10CFTR
SCHEMBL301544 0.84 ALDH1A1 (0.58) TSHRLMNANPC1ALDH1A1HSD17B10
SCHEMBL29480096 0.84 ALDH1A1 (0.58) TSHRLMNANPC1ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108341899-A A kind of catalytic component, preparation method and applications being used for vinyl polymerization or combined polymerization based on alkoxyl magnesium carrier 任丘市利和科技发展有限公司 2018-07-31 CN claimed
CN-119751718-A Dialkoxy magnesium carrier type solid catalyst component for ethylene polymerization or copolymerization, preparation method and application thereof 任丘市利和科技发展有限公司 2025-04-04 CN disclosed
WO-2025020304-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST AND USE OF CATALYST 中国石油天然气股份有限公司 2025-01-30 WO disclosed
CN-119331132-A Catalyst component for olefin polymerization, olefin polymerization catalyst and application thereof 中国石油天然气股份有限公司 2025-01-21 CN disclosed
CN-119331135-A Olefin polymerization catalyst component, olefin polymerization catalyst and application thereof 中国石油天然气股份有限公司 2025-01-21 CN disclosed
CN-114716591-B Catalyst component for propylene polymerization, preparation method and application thereof 任丘市利和科技发展有限公司 2024-05-28 CN disclosed
EP-3645625-B1 HIGH STIFFNESS POLYPROPYLENE IMPACT COPOLYMER EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-03-27 EP disclosed
US-11732067-B2 High stiffness polypropylene impact copolymer EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-22 US disclosed
CN-112574341-B Catalyst component for synthesizing high-rigidity polypropylene, catalyst and preparation method thereof 沧州利和科技发展有限责任公司 2022-11-01 CN disclosed
CN-110997795-B High stiffness polypropylene impact copolymers 埃克森美孚化学专利公司 2022-10-04 CN disclosed
US-20040077488-A1 Polymerization catalyst for olefins and process for polymerization of olefins TOHO TITANIUM CO., LTD. (JP) 2004-04-22 US disclosed
EP-1270604-A1 CATALYST FOR OLEFIN POLYMERIZATION Toho Titanium Co., Ltd. (JP) 2003-01-02 EP disclosed
US-20020193244-A1 Catalyst for olefin polymerization TOHO TITANIUM CO., LTD. (JP) 2002-12-19 US disclosed
EP-0773240-B1 Solid catalyst component for polymerizing olefins and catalyst for polymerization of olefins TOHO TITANIUM CO LTD (JP) 2001-08-22 EP disclosed
EP-0811639-B1 SOLID CATALYTIC COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST TOHO TITANIUM CO LTD (JP) 2001-08-01 EP disclosed
EP-0773241-A2 Solid catalyst component for polymerizing olefins and catalyst for polymerization of olefins TOHO TITANIUM CO., LTD. (JP) 1997-05-14 EP disclosed
EP-0773240-A2 Solid catalyst component for polymerizing olefins and catalyst for polymerization of olefins TOHO TITANIUM CO., LTD. (JP) 1997-05-14 EP disclosed
EP-0665243-A2 Catalyst for polymerization of olefins and process for polymerization of olefins using the same TOHO TITANIUM CO., LTD. (JP) 1995-08-02 EP disclosed
US-4098981-A POLYMERIZATION OF VINYL MONOMERS EMPLOYING LIQUID ACYL SULFONYL PEROXIDE FORMULATIONS DERIVED FROM SOLID ACYL ALKYLSULFONYL PEROXIDES PENNWALT CORPORATION (US) 1978-07-04 US disclosed
US-4043940-A FREE-RADICAL INITIATORS PENNWALT CORPORATION (US) 1977-08-23 US disclosed