Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.58 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.58 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634295 | 0.83 | SPHK2 (0.58) | SPHK2SPHK1MMP13HPGDPOLB | |
| SCHEMBL620074 | 0.82 | POLB (0.66) | SPHK2SPHK1MMP13HPGDPOLB | |
| SCHEMBL21015330 | 0.80 | SPHK2 (0.54) | SPHK2SPHK1MMP13HPGDPOLB | |
| SCHEMBL8142775 | 0.78 | POLB (0.58) | SPHK2SPHK1MMP13HPGDPOLB | |
| SCHEMBL8404665 | 0.77 | PLK1 (0.61) | SPHK2SPHK1MMP13HPGDPOLB | |
| SCHEMBL5803734 | 0.77 | HPGD (0.53) | SPHK2SPHK1MMP13HPGDPOLB | |
| SCHEMBL8982300 | 0.77 | POLB (0.57) | SPHK2SPHK1MMP13HPGDPOLB | |
| SCHEMBL23146038 | 0.77 | HPGD (0.53) | SPHK2SPHK1MMP13HPGDPOLB | |
| SCHEMBL8404664 | 0.77 | HDAC3 (0.61) | SPHK2SPHK1MMP13HPGDPOLB | |
| SCHEMBL5803733 | 0.77 | HPGD (0.53) | SPHK2SPHK1MMP13HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831841-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T Global Inc. (US) | 2021-06-09 | — | — | EP | disclosed |