SCHEMBL620074

SCHEMBL620074

O=C(NCCO)c1ccc(C(=O)NCCO)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.66
HPGD P15428 2/20 0.66
HTT P42858 1/20 0.66
MMP13 P45452 1/20 0.65
CA12 O43570 1/20 0.62
CA1 P00915 1/20 0.62
CA2 P00918 1/20 0.62
CA9 Q16790 1/20 0.62
CA14 Q9ULX7 1/20 0.62
ALDH1A1 P00352 3/20 0.55
KDM4E B2RXH2 2/20 0.54
MAPK1 P28482 1/20 0.53
LMNA P02545 1/20 0.53
CYP1A2 P05177 1/20 0.53
TSHR P16473 1/20 0.53
NFKB1 P19838 1/20 0.53
MAOB P27338 1/20 0.53
SPHK2 Q9NRA0 1/20 0.53
SPHK1 Q9NYA1 1/20 0.53
MEN1 O00255 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8142775 0.91 POLB (0.58) POLBHPGDHTTMMP13CA12
SCHEMBL23471096 0.91 POLB (0.58) POLBHPGDHTTMMP13CA12
SCHEMBL12913509 0.89 MAOB (0.70) POLBHPGDHTTMMP13CA12
SCHEMBL5636368 0.89 NPC1 (0.62) POLBHPGDHTTMMP13CA12
SCHEMBL9585652 0.89 CYP1A2 (0.70) POLBHPGDHTTMMP13CA12
SCHEMBL24386099 0.89 POLB (0.56) POLBHPGDHTTMMP13CA12
SCHEMBL853629 0.89 KDM4E (0.61) POLBHPGDHTTMMP13CA12
SCHEMBL12893201 0.89 MMP13 (0.60) POLBHPGDHTTMMP13CA12
SCHEMBL1665183 0.89 OGG1 (0.59) POLBHPGDHTTMMP13CA12
SCHEMBL3176444 0.89 POLB (0.56) POLBHPGDHTTMMP13CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119264003-A Chemical degradation and resource utilization method for waste polyester plastics 浙江恒丰新材料有限公司 2025-01-07 CN claimed
CN-116535470-A Polypeptide with anti-mycobacterium tuberculosis activity, preparation method and application thereof 南京农业大学 2023-08-04 CN claimed
CN-116514925-A Mycobacterium tuberculosis-resistant polypeptide, preparation method and application thereof 南京农业大学 2023-08-01 CN claimed
US-4687834-A Polyester imides and method for producing same HULS AKTIENGESELLSCHAFT (DE) 1987-08-18 US claimed
US-4549010-A Bioerodible poly(ortho ester) thermoplastic elastomer from diketene diacetal MERCK & CO., INC. (US) 1985-10-22 US claimed
CN-121517668-A Polyurethane acrylate resin, preparation method thereof and application thereof in ACF adhesive film 合肥中聚和成光电材料股份有限公司 2026-02-13 CN disclosed
CN-116514925-B Mycobacterium tuberculosis-resistant polypeptide, preparation method and application thereof 南京农业大学 2025-11-04 CN disclosed
CN-116535470-B Polypeptide with anti-mycobacterium tuberculosis activity, preparation method and application thereof 南京农业大学 2025-11-04 CN disclosed
CN-118955281-B Method for catalyzing and degrading polyester by using alkaline ionic liquid 东华大学 2025-03-21 CN disclosed
CN-119264003-A Chemical degradation and resource utilization method for waste polyester plastics 浙江恒丰新材料有限公司 2025-01-07 CN disclosed
CN-119264003-A Chemical degradation and resource utilization method for waste polyester plastics 浙江恒丰新材料有限公司 2025-01-07 CN disclosed
CN-118955281-A Method for catalyzing and degrading polyester by using alkaline ionic liquid 东华大学 2024-11-15 CN disclosed
EP-0222980-A2 Polyester imide and process for its preparation HÜLS AKTIENGESELLSCHAFT (DE) 1987-05-27 EP disclosed
EP-0193346-A2 Process for forming a hot melt composition GENESCO INC. (US) 1986-09-03 EP disclosed
US-4608418-A POLYURETHANES WITH PLASTICIZERS AND CHAIN EXTENDERS GENSCO INC. (US) 1986-08-26 US disclosed
US-4549010-A Bioerodible poly(ortho ester) thermoplastic elastomer from diketene diacetal MERCK & CO., INC. (US) 1985-10-22 US disclosed
EP-0009866-B1 PHENOLIC ESTERAMIDE ANTIOXIDANTS AND THEIR USE UNIROYAL, INC. (US) 1982-08-04 EP disclosed
US-4305868-A Phenolic esteramide antioxidants UNIROYAL, INC. (US) 1981-12-15 US disclosed
EP-0009866-A1 Phenolic esteramide antioxidants and their use UNIROYAL, INC. (US) 1980-04-16 EP disclosed
US-4174455-A CHAIN EXTENSION, CROSSLINKING AND/OR CURINF OF POLYUREAS, POLYURETHANES, AND EPOXY RESINS CIBA-GEIGY CORPORATION (US) 1979-11-13 US disclosed