Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23471010 | 0.94 | HTT (0.45) | HTTSMN1; SMN2KDM4EGAAALDH1A1 | |
| SCHEMBL23471011 | 0.92 | HTT (0.44) | HTTSMN1; SMN2KDM4EGAAALDH1A1 | |
| SCHEMBL23471200 | 0.81 | PRSS1 (0.44) | PRSS1CTSGCTRB1CMA1ADORA2A | |
| SCHEMBL21015349 | 0.81 | PRSS1 (0.39) | HTTSMN1; SMN2KDM4EGAAPRSS1 | |
| SCHEMBL19634276 | 0.80 | CYP2C9 (0.50) | SMN1; SMN2KDM4EGAAALDH1A1CA12 | |
| SCHEMBL21015350 | 0.80 | MAPK14 (0.37) | HTTSMN1; SMN2KDM4EGAACA12 | |
| SCHEMBL23471223 | 0.79 | EPHX2 (0.44) | HTTKDM4EGAALMNAPOLB | |
| SCHEMBL17865785 | 0.77 | ADORA2A (0.59) | SMN1; SMN2ALDH1A1LMNANFKB1NFKB2 | |
| SCHEMBL18652187 | 0.76 | KDM4E (0.55) | HTTSMN1; SMN2KDM4EGAAALDH1A1 | |
| SCHEMBL4882979 | 0.76 | CNR2 (0.53) | HTTKDM4EGAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831841-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T Global Inc. (US) | 2021-06-09 | — | — | EP | disclosed |