Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NSD2 | O96028 | 1/20 | 0.55 |
| ▸ | ALPL | P05186 | 1/20 | 0.55 |
| ▸ | ALPI | P09923 | 1/20 | 0.55 |
| ▸ | ALPG | P10696 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | TOP1 | P11387 | 3/20 | 0.47 |
| ▸ | TOP2A | P11388 | 3/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24871936 | 0.89 | KDM4E (0.55) | KDM4ELMNATDP1POLBGAA | |
| SCHEMBL18652182 | 0.82 | HDAC6 (0.55) | KDM4EPOLBGAAL3MBTL1MAPT | |
| SCHEMBL5924542 | 0.80 | CNR2 (0.46) | KDM4ELMNAMAPTHTTADORA2A | |
| SCHEMBL23471200 | 0.79 | PRSS1 (0.44) | NPC1ADORA2ACNR1CNR2 | |
| SCHEMBL328703 | 0.79 | KDM4E (0.61) | KDM4ELMNATDP1POLBGAA | |
| SCHEMBL3894629 | 0.78 | CNR2 (0.57) | LMNAL3MBTL1ALDH1A1MAPTHTT | |
| SCHEMBL13286830 | 0.78 | KDM4E (0.65) | KDM4ELMNATDP1POLBGAA | |
| SCHEMBL17865785 | 0.78 | ADORA2A (0.59) | LMNAL3MBTL1ALDH1A1NFKB1NFKB2 | |
| SCHEMBL23471122 | 0.76 | HTT (0.49) | KDM4ELMNATDP1POLBGAA | |
| SCHEMBL23471223 | 0.76 | EPHX2 (0.44) | KDM4ELMNAPOLBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170081346-A1 | MESOSCOPIC MATERIALS COMPRISED OF ORDERED SUPERLATTICES OF MICROPOROUS METAL-ORGANIC FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170081346-A1 | MESOSCOPIC MATERIALS COMPRISED OF ORDERED SUPERLATTICES OF MICROPOROUS METAL-ORGANIC FRAMEWORKS | MCM2, YTHDF2, MCM6 | KDM4E 1665/4885LMNA 3286/4885TDP1 3932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.