SCHEMBL23471607

SCHEMBL23471607

CC1(C)c2ccccc2-c2cc(N(c3ccccc3)c3cccc(C(=C(c4ccccc4)c4ccccc4)c4ccccc4)c3)ccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 15/20 0.35
L3MBTL1 Q9Y468 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.32
THRB P10828 1/20 0.31
MLNR O43193 1/20 0.31
NR1I2 O75469 1/20 0.31
CHRM2 P08172 1/20 0.31
ADRB1 P08588 1/20 0.31
HTR1A P08908 1/20 0.31
ADRA2A P08913 1/20 0.31
CHRM1 P11229 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23471605 0.92 MEN1 (0.35) PDK2TDP1ALDH1A1MAPTKMT2A
SCHEMBL23471612 0.88 PDK2 (0.38) PDK2
SCHEMBL22000743 0.87 ALDH1A1 (0.40) PDK2L3MBTL1TDP1KDM4EALDH1A1
SCHEMBL22000330 0.87 ALDH1A1 (0.40) PDK2L3MBTL1TDP1KDM4EALDH1A1
SCHEMBL18650199 0.87 ALDH1A1 (0.42) PDK2L3MBTL1TDP1KDM4EALDH1A1
SCHEMBL14681292 0.87 ALDH1A1 (0.42) PDK2L3MBTL1TDP1KDM4EALDH1A1
SCHEMBL23471566 0.86 MEN1 (0.34) PDK2ALDH1A1KMT2A
SCHEMBL23480217 0.86 PDK2 (0.33) PDK2L3MBTL1TDP1KMT2ATHRB
SCHEMBL21760466 0.85 PDK2 (0.47) PDK2CYP3A4KMT2A
SCHEMBL23471567 0.85 PDK2 (0.40) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210175436-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-06-10 US disclosed
EP-3831807-A2 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE Samsung Display Co., Ltd. (KR) 2021-06-09 EP disclosed