⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434969 | 0.94 | — | — | |
| SCHEMBL5540533 | 0.85 | — | — | |
| SCHEMBL5536060 | 0.85 | — | — | |
| SCHEMBL5536758 | 0.85 | — | — | |
| SCHEMBL5542071 | 0.85 | — | — | |
| SCHEMBL5541018 | 0.85 | — | — | |
| SCHEMBL5546067 | 0.85 | — | — | |
| SCHEMBL5546821 | 0.85 | — | — | |
| SCHEMBL11021303 | 0.80 | LMNA (0.37) | — | |
| SCHEMBL5147150 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008502-B2 | Thiazoline acid derivatives | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2011-08-30 | — | — | US | disclosed |
| US-20100094016-A1 | Thiazoline acid derivatives | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-04-15 | — | — | US | disclosed |
| EP-1380577-B1 | Thiazoline acid derivatives | UNIV FLORIDA (US) | 2009-11-18 | — | — | EP | disclosed |
| EP-2096112-A2 | Thiazoline acid derivatives | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2009-09-02 | — | — | EP | disclosed |
| US-7531563-B2 | Thiazoline acid derivatives | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2009-05-12 | — | — | US | disclosed |
| US-20070238767-A1 | Thiazoline acid derivatives | FOUNDATION, INC. (US) | 2007-10-11 | — | — | US | disclosed |
| US-7126004-B2 | Thiazoline acid derivatives | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2006-10-24 | — | — | US | disclosed |
| US-RE39132-E1 | Thiazoline acid derivatives | UNIVERSITY OF FLORIDA, RESEARCH FOUNDATION, INC. (US) | 2006-06-13 | — | — | US | disclosed |
| EP-1109795-B1 | THIAZOLINE ACID DERIVATIVES | UNIV FLORIDA (US) | 2006-02-08 | — | — | EP | disclosed |
| US-20050033057-A1 | Thiazoline acid derivatives | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2005-02-10 | — | — | US | disclosed |
| US-6525080-B1 | Chelators or sequestrants for trivalent metals such as iron, aluminum and chromium; preventing deposition in and eliination from tissues; haemochromatosis, haemosiderosis, cirrhosis | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2003-02-25 | — | — | US | disclosed |
| US-6521652-B1 | Diagnosing and treating pathological conditions associated with an excess of trivalent metals | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2003-02-18 | — | — | US | disclosed |
| WO-2000012493-A9 | THIAZOLINE ACID DERIVATIVES | UNIV FLORIDA (US) | 2002-04-11 | — | — | WO | disclosed |
| EP-1109795-A1 | THIAZOLINE ACID DERIVATIVES | UNIVERSITY OF FLORIDA (US) | 2001-06-27 | — | — | EP | disclosed |
| US-6083966-A | FOR DIAGNOSING AND TREATING PATHOLOGICAL CONDITIONS ASSOCIATED WITH AN EXCESS OF TRIVALENT METALS IN HUMANS AND ANIMALS; TREATMENT OF THALASSEMIA, ANEMIA | UNIVERSITY OF FLORIDA (US) | 2000-07-04 | — | — | US | disclosed |
| WO-2000012493-A1 | THIAZOLINE ACID DERIVATIVES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2000-03-09 | — | — | WO | disclosed |
| EP-0900209-A1 | THIAZOLINE ACID DERIVATIVES | UNIVERSITY OF FLORIDA (US) | 1999-03-10 | — | — | EP | disclosed |
| US-5840739-A | Thiazoline acid derivatives | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1998-11-24 | — | — | US | disclosed |
| WO-1997036885-A1 | THIAZOLINE ACID DERIVATIVES | UNIVERSITY OF FLORIDA (US) | 1997-10-09 | — | — | WO | disclosed |
| WO-1994011367-A1 | 2-(PYRID-2'-YL)-2-THIAZOLINE-4(S)-CARBOXYLIC ACID DERIVATIVES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INC. (US) | 1994-05-26 | — | — | WO | disclosed |