Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15470269 | 0.88 | TLR7 (0.44) | TLR7TLR8KCNH2 | |
| SCHEMBL20219282 | 0.85 | KCNH2 (0.37) | TLR7TLR8KCNH2 | |
| SCHEMBL15470255 | 0.83 | TLR7 (0.42) | TLR7TLR8KCNH2 | |
| SCHEMBL23472236 | 0.83 | KCNH2 (0.43) | TLR7TLR8KCNH2 | |
| SCHEMBL15470234 | 0.82 | TLR7 (0.43) | TLR7TLR8 | |
| SCHEMBL20219614 | 0.82 | TLR7 (0.43) | TLR7TLR8 | |
| SCHEMBL23472692 | 0.81 | KCNH2 (0.34) | TLR7TLR8KCNH2 | |
| SCHEMBL15469988 | 0.81 | KCNH2 (0.57) | TLR7TLR8KCNH2 | |
| SCHEMBL20219557 | 0.81 | KCNH2 (0.57) | TLR7TLR8KCNH2 | |
| SCHEMBL20386791 | 0.81 | KCNH2 (0.46) | TLR7TLR8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |