Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 13/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 13/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15470073 | 0.93 | TLR7 (0.52) | TLR7TLR8L3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL20219397 | 0.92 | TLR7 (0.48) | TLR7TLR8L3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL20219479 | 0.88 | TLR7 (0.41) | TLR7TLR8L3MBTL1 | |
| SCHEMBL23472139 | 0.87 | TLR8 (0.56) | TLR7TLR8L3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL23472653 | 0.86 | TLR8 (0.55) | TLR7TLR8L3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL23472677 | 0.85 | TLR8 (0.47) | TLR7TLR8L3MBTL1 | |
| SCHEMBL15469985 | 0.85 | TLR8 (0.54) | TLR7TLR8L3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL13195051 | 0.85 | TLR7 (0.68) | TLR7TLR8L3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL13195073 | 0.84 | TLR7 (0.53) | TLR7TLR8L3MBTL1 | |
| SCHEMBL20219355 | 0.84 | TLR7 (0.64) | TLR7TLR8CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |