Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20413288 | 0.85 | HPGD (0.39) | HPGDKCNH2TMEM97SIGMAR1TAS1R3 | |
| SCHEMBL15470255 | 0.82 | TLR7 (0.42) | KCNH2TLR8TLR7 | |
| SCHEMBL20413292 | 0.81 | TAS1R3 (0.39) | HPGDKCNH2TAS1R3TAS1R1TLR8 | |
| SCHEMBL20386758 | 0.79 | HPGD (0.39) | HPGDTAS1R3TAS1R1CALM1HDAC1 | |
| SCHEMBL15470269 | 0.78 | TLR7 (0.44) | KCNH2TLR8TLR7 | |
| SCHEMBL14376435 | 0.76 | TLR7 (0.42) | HPGDTLR8TLR7 | |
| SCHEMBL20413290 | 0.74 | TAS1R3 (0.40) | HPGDTAS1R3TAS1R1KMT2AMEN1 | |
| SCHEMBL21769268 | 0.72 | KCNH2 (0.42) | KCNH2SIGMAR1TLR8TLR7 | |
| SCHEMBL15470234 | 0.72 | TLR7 (0.43) | TAS1R3TAS1R1TLR8TLR7KDM4E | |
| SCHEMBL20219614 | 0.72 | TLR7 (0.43) | TAS1R3TAS1R1TLR8TLR7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |