Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.56 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15470025 | 0.90 | CYP1A2 (0.53) | TLR7TLR8CYP1A2CYP2D6L3MBTL1 | |
| SCHEMBL13195727 | 0.89 | TLR7 (0.57) | TLR7TLR8CYP1A2CYP2D6L3MBTL1 | |
| SCHEMBL15470063 | 0.89 | TLR7 (0.61) | TLR7TLR8CYP1A2CYP2D6L3MBTL1 | |
| SCHEMBL15470045 | 0.86 | TLR7 (0.45) | TLR7TLR8CYP1A2L3MBTL1 | |
| SCHEMBL13195128 | 0.86 | TLR8 (0.62) | TLR7TLR8CYP1A2L3MBTL1 | |
| SCHEMBL13195825 | 0.86 | L3MBTL1 (0.57) | TLR7TLR8L3MBTL1 | |
| SCHEMBL13195687 | 0.86 | L3MBTL1 (0.57) | TLR7TLR8CYP1A2L3MBTL1 | |
| SCHEMBL23472495 | 0.86 | TLR7 (0.49) | TLR7TLR8L3MBTL1 | |
| SCHEMBL13195707 | 0.86 | TLR7 (0.54) | TLR7TLR8CYP1A2CYP2D6L3MBTL1 | |
| SCHEMBL15470018 | 0.85 | TLR7 (0.49) | TLR7TLR8CYP1A2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |