SCHEMBL234731

SCHEMBL234731

c1nc2c([nH]1)CCCC2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4076784 0.98 ADRA1A (0.41)
SCHEMBL2946130 0.98 ADRA1A (0.41)
SCHEMBL3309997 0.98 ADRA1A (0.41)
Benzimidazole SCHEMBL7463429 0.80 ADRA1A (0.41)
SCHEMBL550173 0.76 ADRA1A (0.40)
SCHEMBL31698792 0.76 ADRA1A (0.33)
SCHEMBL19661014 0.72 ADRA1A (0.47)
SCHEMBL12082637 0.72 AKT1 (0.39)
SCHEMBL7977088 0.70
SCHEMBL399938 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 537 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4704830-A2 MRGPRX2 INHIBITORS AND METHODS OF USE THEREOF Septerna, Inc. (US) 2026-03-11 EP claimed
US-20250257089-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2025-08-14 US claimed
US-12324349-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2025-06-03 US claimed
US-20250113726-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2025-04-03 US claimed
EP-4524144-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2025-03-19 EP claimed
CN-119638752-A Organometallic compound, organic light-emitting device, electronic apparatus, and consumer product 三星显示有限公司 2025-03-18 CN claimed
EP-4486698-A1 EMM-73 MOLECULAR SIEVE COMPOSITIONS, SYNTHESES, AND USES ExxonMobil Technology and Engineering Company (US) 2025-01-08 EP claimed
US-20240425379-A1 EMM-73 MOLECULAR SIEVE COMPOSITIONS, SYNTHESES, AND USES ExxonMobil Technology and Engineering Company 2024-12-26 US claimed
EP-4466224-A1 EMM-70 ZEOLITE COMPOSITIONS, SYNTHESES, AND USES ExxonMobil Technology and Engineering Company (US) 2024-11-27 EP claimed
WO-2024226914-A2 MRGPRX2 ANTAGONISTS AND METHODS OF USE THEREOF SEPTERNA, INC. (US) 2024-10-31 WO claimed
WO-2003099276-A1 1,1-DISUBSTITUTED CYCLOALKYL DERIVATIVES AS FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2003-12-04 WO claimed
US-20030004340-A1 New 4-arylpiperidine derivatives for the treatment of pruritus GIBSON STEPHEN PAUL (GB) 2003-01-02 US claimed
EP-1072601-A2 4-arylpiperidine derivatives for the treatment of pruritus PFIZER INC. (US) 2001-01-31 EP claimed
EP-1032569-A1 IMIDAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF SANOFI-SYNTHELABO (FR) 2000-09-06 EP claimed
WO-1999025710-A1 IMIDAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF SANOFI-SYNTHELABO (FR) 1999-05-27 WO claimed
EP-0376624-B1 4,5,6,7-Tetrahydrobenzimidazole derivatives and their preparation YAMANOUCHI PHARMA CO LTD (JP) 1994-09-14 EP claimed
US-4977175-A GASTROINTESTINAL DISORDERS, ANTIEMETICS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1990-12-11 US claimed
EP-0376624-A1 4,5,6,7-Tetrahydrobenzimidazole derivatives and their preparation YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1990-07-04 EP claimed
US-4847251-A CARDIOVASCULAR DISORDERS BOEHRINGER MANNHEIM GMBH (DE) 1989-07-11 US claimed
EP-0076530-B1 NOVEL N-(3-HYDROXY-4-PIPERIDINYL)BENZAMIDE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 1985-12-11 EP claimed