Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 10/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21647154 | 0.87 | TERT (0.60) | TERTCYP1A1CYP1B1ALDH1A1CYP3A4 | |
| SCHEMBL23473366 | 0.86 | TERT (0.45) | TERTCYP1A1CYP1B1ALDH1A1CYP3A4 | |
| SCHEMBL23473437 | 0.70 | USP8 (0.58) | TERTCYP1A1CYP1B1CYP3A4CYP2C19 | |
| SCHEMBL22789421 | 0.69 | TERT (0.66) | TERTCYP1A1CYP1B1ALDH1A1CYP3A4 | |
| SCHEMBL21647173 | 0.69 | TERT (0.66) | TERTCYP1A1CYP1B1ALDH1A1CYP3A4 | |
| SCHEMBL22772266 | 0.69 | TERT (0.62) | TERTCYP1A1CYP1B1ALDH1A1CYP3A4 | |
| SCHEMBL21647175 | 0.68 | TERT (0.60) | TERTCYP1A1CYP1B1ALDH1A1CYP3A4 | |
| SCHEMBL23473424 | 0.68 | USP8 (0.56) | TERTCYP1A1CYP1B1ALDH1A1CYP3A4 | |
| SCHEMBL21647164 | 0.68 | TERT (0.57) | TERTCYP1A1CYP1B1ALDH1A1CYP3A4 | |
| SCHEMBL21647151 | 0.68 | TERT (0.57) | TERTCYP1A1CYP1B1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831821-A1 | COMPOUND FOR TREATING NERVOUS SYSTEM DISEASES AND USE THEREOF | Shaanxi Micot Technology Limited Company (CN) | 2021-06-09 | — | — | EP | disclosed |