SCHEMBL23475938

SCHEMBL23475938

O=C(CCOCCOCCNC(=O)CCOCCOCCNC(=O)CCOCCOCCNC(=O)[C@H](CCCNC(=O)CBr)NC(=O)CBr)NO

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.46
▸ FOLH1 Q04609 3/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ SIRT2 Q8IXJ6 2/20 0.33
▸ GLO1 Q04760 1/20 0.33
▸ EPOR P19235 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23489665 1.00 GLP1R (0.46) GLP1RFOLH1MEN1KMT2ASIRT2
SCHEMBL27436089 0.90 GLP1R (0.50) GLP1RMEN1KMT2ASIRT2
SCHEMBL23475913 0.87 GLP1R (0.62) GLP1RSIRT2
SCHEMBL18202629 0.87 GLP1R (0.62) GLP1RSIRT2
SCHEMBL23475930 0.87 GLP1R (0.62) GLP1RSIRT2
SCHEMBL27436033 0.87 GLP1R (0.62) GLP1RSIRT2
SCHEMBL23475961 0.85 GLP1R (0.57) GLP1RFOLH1SIRT2GLO1EPOR
SCHEMBL23475890 0.85 GLP1R (0.57) GLP1RFOLH1SIRT2GLO1EPOR
SCHEMBL16830716 0.85 GLP1R (0.57) GLP1RFOLH1SIRT2GLO1EPOR
SCHEMBL23475979 0.85 GLP1R (0.57) GLP1RFOLH1SIRT2GLO1EPOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021113535-A1 PEPTIDE CONJUGATES AND METHODS OF USE THE SCRIPPS RESEARCH INSTITUTE (US) 2021-06-10 — — WO disclosed
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