Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopentanamine SCHEMBL8188030 | 0.95 | DNM1 (0.42) | CYP1A2DNM1MEN1KMT2AALDH1A1 | |
| Cyclohexylamine SCHEMBL28135465 | 0.93 | DNM1 (0.52) | CYP1A2DNM1MEN1KMT2AALDH1A1 | |
| Dodecylamine SCHEMBL11756736 | 0.91 | DNM1 (0.56) | CYP1A2DNM1MEN1KMT2AALDH1A1 | |
| Cyclohexylamine SCHEMBL6657888 | 0.91 | DNM1 (0.56) | CYP1A2DNM1MEN1KMT2AALDH1A1 | |
| Cycloheptanamine SCHEMBL18263635 | 0.91 | DNM1 (0.56) | CYP1A2DNM1MEN1KMT2AALDH1A1 | |
| Cyclohexylamine SCHEMBL3138481 | 0.91 | DNM1 (0.56) | CYP1A2DNM1MEN1KMT2AALDH1A1 | |
| Cyclohexylamine SCHEMBL6865056 | 0.91 | DNM1 (0.56) | CYP1A2DNM1MEN1KMT2AALDH1A1 | |
| Decylamine SCHEMBL3259417 | 0.91 | DNM1 (0.56) | CYP1A2DNM1MEN1KMT2AALDH1A1 | |
| Cyclohexylamine SCHEMBL6865558 | 0.91 | DNM1 (0.56) | CYP1A2DNM1MEN1KMT2AALDH1A1 | |
| Octadecylamine SCHEMBL4528802 | 0.91 | DNM1 (0.56) | CYP1A2DNM1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263854-A1 | Improved Process For The Preparation Of Endothelin Receptor Antagonists | MSN LABORATORIES LIMITED (IN) | 2011-10-27 | — | — | US | claimed |
| EP-2350024-A2 | IMPROVED PROCESS FOR THE PREPARATION OF ENDOTHELIN RECEPTOR ANTAGONISTS | MSN Laboratories Limited (IN) | 2011-08-03 | — | — | EP | claimed |
| WO-2010070658-A2 | IMPROVED PROCESS FOR THE PREPARATION OF ENDOTHELIN RECEPTOR ANTAGONISTS | MSN LABORATORIES LIMITED (IN) | 2010-06-24 | — | — | WO | claimed |
| CN-106146416-A | Nitrogen replaces 3 oxo 6 substituted-tetrahydro quinoxaline structural compounds, its preparation method and medical usage thereof | 河南大学 | 2016-11-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263854-A1 | Improved Process For The Preparation Of Endothelin Receptor Antagonists | EDNRA, EDNRB, ECE1 | CYP1A2 758/4885DNM1 1059/4885MEN1 1705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.