Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | CTSB | P07858 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | AGER | Q15109 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | DDX3X | O00571 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12254297 | 0.90 | TGFBR1 (0.35) | TGFBR1ACVR1CTSLCTSBCTSS | |
| SCHEMBL2348986 | 0.90 | TGFBR1 (0.35) | TGFBR1ACVR1CTSLCTSBCTSS | |
| SCHEMBL2383098 | 0.90 | TGFBR1 (0.35) | TGFBR1ACVR1CTSLCTSBCTSS | |
| SCHEMBL2348979 | 0.90 | TGFBR1 (0.35) | TGFBR1ACVR1CTSLCTSBCTSS | |
| SCHEMBL2382089 | 0.90 | TGFBR1 (0.40) | TGFBR1ACVR1CTSLCTSBCTSS | |
| SCHEMBL2382115 | 0.90 | TGFBR1 (0.40) | TGFBR1ACVR1CTSLCTSBCTSS | |
| SCHEMBL2382093 | 0.90 | TGFBR1 (0.40) | TGFBR1ACVR1CTSLCTSBCTSS | |
| SCHEMBL12254293 | 0.90 | TGFBR1 (0.35) | TGFBR1ACVR1CTSLCTSBCTSS | |
| Hydrochloric Acid SCHEMBL2352956 | 0.90 | TGFBR1 (0.35) | TGFBR1ACVR1CTSLCTSBCTSS | |
| Hydrochloric Acid SCHEMBL2349370 | 0.90 | TGFBR1 (0.35) | TGFBR1ACVR1CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536283-A1 | PHENYL-HETEROARYL DERIVATIVES AND METHODS OF USE THEREOF | TransTech Pharma, Inc (US) | 2012-12-26 | — | — | EP | disclosed |
| WO-2011103091-A1 | PHENYL-HETEROARYL DERIVATIVES AND METHODS OF USE THEREOF | TRANSTECH PHARMA, INC. (US) | 2011-08-25 | — | — | WO | disclosed |