Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 3/20 | 0.58 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | SCN1A | P35498 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.58 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.50 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10982102 | 0.98 | MAPK1 (0.56) | ALDH1A1SIGMAR1MAPK1CYP1A2CHRM2 | |
| SCHEMBL5251269 | 0.98 | ALDH1A1 (0.59) | ALDH1A1SIGMAR1MAPK1CYP1A2CHRM2 | |
| SCHEMBL40487 | 0.98 | ALDH1A1 (0.59) | ALDH1A1SIGMAR1MAPK1CYP1A2CHRM2 | |
| Bromide SCHEMBL27876655 | 0.96 | MAPK1 (0.54) | ALDH1A1SIGMAR1MAPK1CYP1A2CHRM2 | |
| Bromide SCHEMBL27860070 | 0.96 | MAPK1 (0.54) | ALDH1A1SIGMAR1MAPK1CYP1A2CHRM2 | |
| Bromide SCHEMBL28503801 | 0.96 | MAPK1 (0.54) | ALDH1A1SIGMAR1MAPK1CYP1A2CHRM2 | |
| SCHEMBL10721706 | 0.95 | MAPK1 (0.58) | ALDH1A1SIGMAR1MAPK1CYP1A2CHRM2 | |
| SCHEMBL1262440 | 0.95 | MAPK1 (0.58) | ALDH1A1SIGMAR1MAPK1CYP1A2CHRM2 | |
| SCHEMBL11479545 | 0.95 | MAPK1 (0.58) | ALDH1A1SIGMAR1MAPK1CYP1A2CHRM2 | |
| SCHEMBL351640 | 0.95 | MAPK1 (0.58) | ALDH1A1SIGMAR1MAPK1CYP1A2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1698631-B1 | IONIC LIQUID, METHOD FOR PRODUCING SAME, DOUBLE LAYER CAPACITOR COMPRISING SAME, AND LITHIUM BATTERY | NAT INST OF ADVANCED IND SCIEN (JP) | 2011-08-10 | — | — | EP | disclosed |
| US-20070099079-A1 | Ionic liquid, method for producing same, double layer capacitor comprising same, and lithium battery | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2007-05-03 | — | — | US | disclosed |
| EP-1698631-A1 | IONIC LIQUID, METHOD FOR PRODUCING SAME, DOUBLE LAYER CAPACITOR COMPRISING SAME, AND LITHIUM BATTERY | National Institute of Advanced Industrial Science and Technology (JP) | 2006-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099079-A1 | Ionic liquid, method for producing same, double layer capacitor comprising same, and lithium battery | CLCN2, CACNA1F, CACNB3 | SIGMAR1 4039/4885CHRM2 909/4885ALDH1A1 3860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.