SCHEMBL234798

SCHEMBL234798

CC(C)CCC(=O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.59
OR51E2 Q9H255 2/20 0.46
MAPK1 P28482 1/20 0.46
SLC13A3 Q8WWT9 1/20 0.46
EGLN1 Q9GZT9 1/20 0.46
GABRP O00591 2/20 0.39
GABRD O14764 2/20 0.39
GABRA1 P14867 2/20 0.39
GABRB1 P18505 2/20 0.39
GABRG2 P18507 2/20 0.39
GABRB3 P28472 2/20 0.39
GABRA5 P31644 2/20 0.39
GABRA3 P34903 2/20 0.39
GABRA2 P47869 2/20 0.39
GABRB2 P47870 2/20 0.39
GABRA4 P48169 2/20 0.39
GABRE P78334 2/20 0.39
GABRA6 Q16445 2/20 0.39
GABRG1 Q8N1C3 2/20 0.39
GABRG3 Q99928 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7615209 0.85 CA1 (0.68) CA1GABRPGABRDGABRA1GABRB1
SCHEMBL2171421 0.84 CA1 (0.48) CA1OR51E2MAPK1SLC13A3EGLN1
SCHEMBL2216359 0.82 KDM4C (0.47) CA1OR51E2MAPK1SLC13A3EGLN1
SCHEMBL11346087 0.81 ALDH1A1 (0.48) CA1OR51E2MAPK1SLC13A3EGLN1
SCHEMBL4947614 0.80 KDM4C (0.50) CA1OR51E2MAPK1SLC13A3EGLN1
SCHEMBL7762810 0.80 KDM4C (0.50) CA1OR51E2MAPK1SLC13A3EGLN1
SCHEMBL8679322 0.78 CA1 (0.52) CA1GABRPGABRDGABRA1GABRB1
SCHEMBL8677168 0.78 CA1 (0.52) CA1GABRPGABRDGABRA1GABRB1
SCHEMBL12077143 0.78 CA1 (0.59) CA1GABRPGABRDGABRA1GABRB1
SCHEMBL8679323 0.78 CA1 (0.52) CA1GABRPGABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113429332-B 3-substituted indole derivative, preparation method thereof and application thereof in antitumor drugs 长春工业大学 2023-12-15 CN claimed
CN-116987722-A Cephalotaxus hainanensis isopropyl malic acid synthetase IPMS1 and application thereof 中国热带农业科学院热带作物品种资源研究所 2023-11-03 CN claimed
CN-116904488-A Cephalotaxus hainanensis glutamic acid aminotransferase AAT1 and application thereof 中国热带农业科学院热带作物品种资源研究所 2023-10-20 CN claimed
US-10450589-B2 Microbial synthesis of aldehydes and corresponding alcohols EASEL BIOTECHNOLOGIES, LLC (US) 2019-10-22 US claimed
EP-2686432-B1 MICROBIAL SYNTHESES OF ALDEHYDES AND CORRESPONDING ALCOHOLS EASEL BIOTECHNOLOGIES LLC (US) 2018-12-26 EP claimed
US-20170283836-A1 Microbial Synthesis Of Aldehydes And Corresponding Alcohols EASEL BIOTECHNOLOGIES, LLC 2017-10-05 US claimed
US-9708631-B2 Microbial synthesis of aldehydes and corresponding alcohols EASEL BIOTECHNOLOGIES, LLC (US) 2017-07-18 US claimed
US-20160130611-A1 Microbial Synthesis Of Aldehydes And Corresponding Alcohols EASEL BIOTECHNOLOGIES, LLC 2016-05-12 US claimed
US-9206443-B2 Microbial synthesis of aldehydes and corresponding alcohols EASEL BIOTECHNOLOGIES, LLC (US) 2015-12-08 US claimed
EP-1874407-B1 SUBSTANCES AND PHARMACEUTICAL COMPOSITIONS FOR THE INHIBITION OF GLYOXALASES AND THEIR USE AS ANTI-FUNGAL AGENTS BIOMAC PRIVATINSTITUT FÜR MEDIZINISCHE UND ZAHNMEDIZINISCHE FORSCHUNG ENTWICKLUNG UND DIAGNOSTIK GMB (DE) 2015-09-09 EP claimed
EP-2686432-A2 MICROBIAL SYNTHESES OF ALDEHYDES AND CORRESPONDING ALCOHOLS Easel Biotechnologies, LLC (US) 2014-01-22 EP claimed
US-20140011231-A1 Microbial Synthesis Of Aldehydes And Corresponding Alcohols EASEL BIOTECHNOLOGIES, LLC (US) 2014-01-09 US claimed
EP-1877141-B1 SUBSTANCES AND PHARMACEUTICAL COMPOSITIONS FOR THE INHIBITION OF GLYOXALASES AND THEIR USE AGAINST BACTERIA BIOMAC PRIVATINSTITUT FUER MEDIZINISCHE UND ZAHNMEDIZINISCHE FORSCHUNG ENTWICKLUNG UND DIAGNOSTIK GM (DE) 2013-06-12 EP claimed
WO-2012125688-A2 MICROBIAL SYNTHESES OF ALDEHYDES AND CORRESPONDING ALCOHOLS EASEL BIOTECHNOLOGIES, LLC (US) 2012-09-20 WO claimed
US-3959312-A Synthesis of antitumor alkaloid deoxyharringtonine and its precursor 3'-0-(5-methyl-2-oxohexanoyl)-cephalotaxine THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1976-05-25 US claimed
EP-3519579-B1 PROCESSES TO PREPARE ELONGATED 2-KETOACIDS AND C-5-C10 COMPOUNDS THEREFROM VIA GENETIC MODIFICATIONS TO MICROBIAL METABOLIC PATHWAYS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-11-05 EP disclosed
CN-111201321-B Genetically modified isopropyl malate isomerase enzyme complex and preparation of elongated 2-keto acids and C using same5-C10Method for preparing compounds 陶氏环球技术有限责任公司 2024-07-12 CN disclosed
EP-0045977-A2 Components and catalysts for the polymerization of olefins Montedison S.p.A. (IT) 1982-02-17 EP disclosed
EP-0012401-A1 Carboxyalkyl dipeptide derivatives, process for preparing them and pharmaceutical composition containing them MERCK & CO. INC. (US) 1980-06-25 EP disclosed
US-3959312-A Synthesis of antitumor alkaloid deoxyharringtonine and its precursor 3'-0-(5-methyl-2-oxohexanoyl)-cephalotaxine THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1976-05-25 US disclosed