⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL703176 | 0.80 | TSHR (0.32) | — | |
| SCHEMBL19210228 | 0.77 | — | — | |
| SCHEMBL7416284 | 0.75 | — | — | |
| SCHEMBL15290275 | 0.75 | — | — | |
| SCHEMBL2345981 | 0.71 | — | — | |
| SCHEMBL2347832 | 0.69 | — | — | |
| SCHEMBL4777786 | 0.69 | — | — | |
| SCHEMBL31679616 | 0.67 | — | — | |
| SCHEMBL17017282 | 0.67 | — | — | |
| SCHEMBL1699089 | 0.67 | TDP1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050137220-A1 | Beta-carboline compounds and analogues thereof as mitogen-activated protein kinase-activated protein kinase-2 inhibitors | PHARMACIA CORPORATION (US) | 2005-06-23 | — | — | US | claimed |
| EP-0670838-A1 | SUBSTITUTED-PHENYL(N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE)-1H/3H-IMIDAZO 4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1995-09-13 | — | — | EP | claimed |
| US-5359073-A | Substituted-phenyl (N,N'-cycloalkyl/alkyl carboxamide)-1H/3H-imidazo[4,5-b]pyridine compounds as PAF antagonists | G. D. SEARLE & CO. (US) | 1994-10-25 | — | — | US | claimed |
| WO-1994012500-A1 | SUBSTITUTED-PHENYL(N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE)-1H/3H-IMIDAZO[4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1994-06-09 | — | — | WO | claimed |
| US-5262426-A | Treatment of cardiovascular disorders, antiinflammatory agents | G. D. SEARLE & CO. (US) | 1993-11-16 | — | — | US | claimed |
| WO-2023176458-A1 | DISINFECTING COMPOSITION CONTAINING THIAZOLE CARBOXYLIC ACID HYDRAZIDE COMPOUND | 石原産業株式会社 | 2023-09-21 | — | — | WO | disclosed |
| EP-1551885-B1 | PROCESS TO MODIFY POLYMERIC MATERIALS | 3M INNOVATIVE PROPERTIES CO (US) | 2016-02-17 | — | — | EP | disclosed |
| EP-1489061-B1 | PROCESS FOR PRODUCING CYCLIC COMPOUND | NIPPON SODA CO (JP) | 2011-08-31 | — | — | EP | disclosed |
| US-20100048819-A1 | PROCESS TO MODIFY POLYMERIC MATERIALS AND RESULTING COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY | 2010-02-25 | — | — | US | disclosed |
| US-7632916-B2 | Thermally induced graft polymerization in an apparatus by shearing, devolatilization; grafting isoprene-t-butyl methacrylate copolymer with polyoxyethylene glycol methyl ether, forming methacrylic acid/anhydride monomers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-12-15 | — | — | US | disclosed |
| US-7459551-B2 | Method for preparing cyclic compounds | ASUBIO PHARMA CO., LTD. (JP) | 2008-12-02 | — | — | US | disclosed |
| US-20050209450-A1 | Process for producing cyclic compound | NIPPON SODA CO., LTD. (JP) | 2005-09-22 | — | — | US | disclosed |
| CN-1149214-C | Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient | ������������ʽ���� | 2004-05-12 | — | — | CN | disclosed |
| WO-2004013189-A2 | PROCESS TO MODIFY POLYMERIC MATERIALS AND RESULTING COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-02-12 | — | — | WO | disclosed |
| US-20040024130-A1 | Process to modify polymeric materials and resulting compositions | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-05 | — | — | US | disclosed |
| CN-1293674-A | Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient | TORAY INDUSTRIES (JP) | 2001-05-02 | — | — | CN | disclosed |
| WO-1994012500-A1 | SUBSTITUTED-PHENYL(N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE)-1H/3H-IMIDAZO[4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1994-06-09 | — | — | WO | disclosed |
| CN-1085556-A | The 4-pyrimidyl and the pyridinyl derivatives of the indol-3-yl alkylpiperazine of anti-migraine | BRISTOL MYERS SQUIBB CO (US) | 1994-04-20 | — | — | CN | disclosed |
| US-5262426-A | Treatment of cardiovascular disorders, antiinflammatory agents | G. D. SEARLE & CO. (US) | 1993-11-16 | — | — | US | disclosed |
| US-4395418-A | 6-HYDROXYETHYL SUBSTITUTED ANTIBIOTICS | SANKYO COMPANY LIMITED (JP) | 1983-07-26 | — | — | US | disclosed |