⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164728 | 0.75 | — | — | |
| SCHEMBL2348007 | 0.71 | — | — | |
| SCHEMBL25404271 | 0.71 | — | — | |
| SCHEMBL25403562 | 0.71 | — | — | |
| SCHEMBL2343550 | 0.71 | — | — | |
| SCHEMBL3382996 | 0.69 | — | — | |
| SCHEMBL10511347 | 0.69 | — | — | |
| SCHEMBL6238565 | 0.68 | — | — | |
| SCHEMBL11656800 | 0.65 | TRPA1 (0.38) | — | |
| SCHEMBL11656801 | 0.65 | TRPA1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680478-A1 | N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE 4H-IMIDAZO 4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1995-11-08 | — | — | EP | claimed |
| EP-0670838-A1 | SUBSTITUTED-PHENYL(N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE)-1H/3H-IMIDAZO 4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1995-09-13 | — | — | EP | claimed |
| US-5359073-A | Substituted-phenyl (N,N'-cycloalkyl/alkyl carboxamide)-1H/3H-imidazo[4,5-b]pyridine compounds as PAF antagonists | G. D. SEARLE & CO. (US) | 1994-10-25 | — | — | US | claimed |
| WO-1994017063-A1 | N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE 4H-IMIDAZO[4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1994-08-04 | — | — | WO | claimed |
| WO-1994012500-A1 | SUBSTITUTED-PHENYL(N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE)-1H/3H-IMIDAZO[4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1994-06-09 | — | — | WO | claimed |
| US-5304623-A | Comprising a polyetherurethane, a vinyl polymer having pendant siloxy groups and a partially blocked solid polyisocyanate; adhesives; auto windshields; storage stability | SUNSTAR GIKEN KABUSHIKI KAISHA (JP) | 1994-04-19 | — | — | US | claimed |
| US-5262426-A | Treatment of cardiovascular disorders, antiinflammatory agents | G. D. SEARLE & CO. (US) | 1993-11-16 | — | — | US | claimed |
| US-20240191096-A1 | UNDERCOAT AGENT, AND METHOD FOR PRODUCING STRUCTURE INCLUDING PHASE-SEPARATED STRUCTURE | TOKYO OHKA KOGYO CO., LTD. (JP) | 2024-06-13 | — | — | US | disclosed |
| WO-2023176458-A1 | DISINFECTING COMPOSITION CONTAINING THIAZOLE CARBOXYLIC ACID HYDRAZIDE COMPOUND | 石原産業株式会社 | 2023-09-21 | — | — | WO | disclosed |
| US-10676636-B2 | Brush composition, and method of producing structure containing phase-separated structure | TOKYO OHKA KOGYO CO., LTD. (JP) | 2020-06-09 | — | — | US | disclosed |
| US-20180273794-A1 | BRUSH COMPOSITION, AND METHOD OF PRODUCING STRUCTURE CONTAINING PHASE-SEPARATED STRUCTURE | TOKYO OHKA KOGYO CO., LTD. (JP) | 2018-09-27 | — | — | US | disclosed |
| US-9821338-B2 | Method of producing structure containing phase-separated structure utilizing a brush composition comprising PS-PMMA | TOKYO OHKA KOGYO., LTD. (JP) | 2017-11-21 | — | — | US | disclosed |
| US-9776208-B2 | Brush composition, and method of producing structure containing phase-separated structure | TOKYO OHKA KOGYO CO., LTD. (JP) | 2017-10-03 | — | — | US | disclosed |
| US-5061749-A | Polyurethane, vinyl polymer containing siloxy groups, filler and plasticizers | SUNSTAR GIKEN KABUSHIKI KAISHA (JP) | 1991-10-29 | — | — | US | disclosed |
| EP-0239228-B1 | POLYSILOXANE URETHANE COMPOUNDS AND ADHESIVE COMPOSITIONS, AND METHOD OF MAKING AND USING THE SAME | LOCTITE CORPORATION (US) | 1991-09-11 | — | — | EP | disclosed |
| EP-0239228-A2 | Polysiloxane urethane compounds and adhesive compositions, and method of making and using the same | LOCTITE CORPORATION (US) | 1987-09-30 | — | — | EP | disclosed |
| EP-0231932-A2 | Coating resin composition | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1987-08-12 | — | — | EP | disclosed |
| US-4684538-A | BONDING LOW DENSITY POLYETHYLENE | LOCTITE CORPORATION (US) | 1987-08-04 | — | — | US | disclosed |
| US-4543398-A | Ophthalmic devices fabricated from urethane acrylates of polysiloxane alcohols | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-09-24 | — | — | US | disclosed |
| EP-0127321-A1 | Ophthalmic devices fabricated from urethane acrylates of polysiloxane alcohols | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-12-05 | — | — | EP | disclosed |