Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | USP8 | P40818 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | AKT2 | P31751 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12093679 | 0.82 | HTR7 (0.46) | TSHRHTR7GRM4KDM1ATRPA1 | |
| SCHEMBL23268427 | 0.79 | HTR7 (0.41) | TSHRHTR7MPOGRM4KDM1A | |
| SCHEMBL12092900 | 0.77 | TSHR (0.46) | TSHRHTR7GRM4KDM1AUSP8 | |
| SCHEMBL18531472 | 0.76 | TSHR (0.36) | TSHRHTR7MPOGRM4KDM1A | |
| SCHEMBL1964751 | 0.75 | TSHR (0.41) | TSHRHTR7 | |
| SCHEMBL30328346 | 0.75 | TSHR (0.41) | TSHRHTR7GRM4KDM1AAPLNR | |
| SCHEMBL113568 | 0.75 | HTR7 (0.44) | TSHRHTR7GRM4KDM1A | |
| SCHEMBL25028948 | 0.75 | HTR7 (0.65) | TSHRHTR7MPOGRM4KDM1A | |
| SCHEMBL18474383 | 0.75 | TSHR (0.41) | TSHRHTR7MPOGRM4KDM1A | |
| SCHEMBL16511359 | 0.75 | TSHR (0.43) | TSHRGRM4MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113679-A1 | DIMERIC COMPOUNDS AS STING AGONISTS | MERSANA THERAPEUTICS, INC. (US) | 2021-06-10 | — | — | WO | disclosed |