Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 11/20 | 0.76 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | STK17B | O94768 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23480339 | 0.92 | STING1 (0.64) | STING1ABL1 | |
| SCHEMBL23480318 | 0.89 | STING1 (0.69) | STING1ABL1KDM4EGAAMAPT | |
| SCHEMBL23480246 | 0.88 | STING1 (0.68) | STING1ABL1MAPTGLO1 | |
| SCHEMBL21436936 | 0.86 | STING1 (1.00) | STING1 | |
| SCHEMBL23480367 | 0.84 | STING1 (0.72) | STING1KDM4EGAAMAPTMEN1 | |
| SCHEMBL23480319 | 0.84 | STING1 (0.68) | STING1ABL1KDM4EGAAMAPT | |
| SCHEMBL23480394 | 0.82 | STING1 (0.81) | STING1 | |
| SCHEMBL21406155 | 0.82 | STING1 (0.81) | STING1SCD | |
| SCHEMBL23480364 | 0.82 | STING1 (0.65) | STING1ABL1LIPG | |
| SCHEMBL23480326 | 0.81 | STING1 (0.79) | STING1KDM4EGAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113679-A1 | DIMERIC COMPOUNDS AS STING AGONISTS | MERSANA THERAPEUTICS, INC. (US) | 2021-06-10 | — | — | WO | disclosed |