Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 16/20 | 0.64 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23480293 | 0.92 | STING1 (0.76) | STING1ABL1 | |
| SCHEMBL23480354 | 0.90 | STING1 (0.74) | STING1ACHE | |
| SCHEMBL23480393 | 0.83 | STING1 (0.57) | STING1ACHE | |
| SCHEMBL23480318 | 0.82 | STING1 (0.69) | STING1ABL1 | |
| SCHEMBL23480392 | 0.81 | STING1 (0.55) | STING1ACHE | |
| SCHEMBL23480246 | 0.81 | STING1 (0.68) | STING1ABL1 | |
| SCHEMBL21436936 | 0.79 | STING1 (1.00) | STING1 | |
| SCHEMBL23480239 | 0.79 | STING1 (0.68) | STING1ACHE | |
| SCHEMBL23480240 | 0.79 | STING1 (0.74) | STING1 | |
| SCHEMBL23480355 | 0.79 | STING1 (0.67) | STING1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113679-A1 | DIMERIC COMPOUNDS AS STING AGONISTS | MERSANA THERAPEUTICS, INC. (US) | 2021-06-10 | — | — | WO | disclosed |