Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 15/20 | 0.79 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21436936 | 0.89 | STING1 (1.00) | STING1 | |
| SCHEMBL23480394 | 0.84 | STING1 (0.81) | STING1 | |
| SCHEMBL23480326 | 0.83 | STING1 (0.79) | STING1GLO1KDM4EMEN1ALDH1A1 | |
| SCHEMBL31081250 | 0.82 | STING1 (0.83) | STING1KDM4EGAAMAPT | |
| SCHEMBL23480294 | 0.82 | STING1 (0.77) | STING1 | |
| SCHEMBL21406155 | 0.81 | STING1 (0.81) | STING1 | |
| SCHEMBL23480293 | 0.81 | STING1 (0.76) | STING1GLO1KDM4EMEN1ALDH1A1 | |
| SCHEMBL23480383 | 0.80 | STING1 (0.74) | STING1MAOB | |
| SCHEMBL21406183 | 0.80 | STING1 (0.77) | STING1MAOB | |
| SCHEMBL31496318 | 0.80 | STING1 (0.77) | STING1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113679-A1 | DIMERIC COMPOUNDS AS STING AGONISTS | MERSANA THERAPEUTICS, INC. (US) | 2021-06-10 | — | — | WO | disclosed |